Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C25777> ?p ?o ?g. }
- NCIT_C25777 IAO_0000115 "C-C chemokine receptor type 5 (352 aa, ~41 kDa) is encoded by the human CCR5 gene. This protein is involved in the modulation of inflammatory responses and cellular signaling." @default.
- NCIT_C25777 NCIT_NHC0 "C25777" @default.
- NCIT_C25777 NCIT_P100 "601373" @default.
- NCIT_C25777 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C25777 NCIT_P106 "Receptor" @default.
- NCIT_C25777 NCIT_P107 "C-C Chemokine Receptor Type 5" @default.
- NCIT_C25777 NCIT_P108 "C-C Chemokine Receptor Type 5" @default.
- NCIT_C25777 NCIT_P207 "C3711103" @default.
- NCIT_C25777 NCIT_P322 "CTRP" @default.
- NCIT_C25777 NCIT_P366 "C-C_Motif_Chemokine_Receptor-5" @default.
- NCIT_C25777 NCIT_P93 "P51681" @default.
- NCIT_C25777 NCIT_P98 "C-C chemokine receptor type 5 acts as a coreceptor (with T-cell surface glycoprotein CD4 as the primary receptor) for HIV." @default.
- NCIT_C25777 NCIT_P98 "Chemokine (C-C Motif) Receptor 5, encoded by the CCR5 gene, is a member of the beta chemokine receptor family and a seven transmembrane protein similar to G protein-coupled receptor. This receptor is expressed by T cells and macrophages, and is an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene is associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene is also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. (From LocusLink)" @default.
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