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- NCIT_C2583 IAO_0000115 "The maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. Rosiglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), a ligand-activated transcription factor, thereby inducing cell differentiation and inhibiting cell growth and angiogenesis. This agent also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation." @default.
- NCIT_C2583 NCIT_A32 NCIT_C1909 @default.
- NCIT_C2583 NCIT_A6 NCIT_C62076 @default.
- NCIT_C2583 NCIT_A7 NCIT_C34077 @default.
- NCIT_C2583 NCIT_NHC0 "C2583" @default.
- NCIT_C2583 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2583 NCIT_P107 "Rosiglitazone Maleate" @default.
- NCIT_C2583 NCIT_P108 "Rosiglitazone Maleate" @default.
- NCIT_C2583 NCIT_P175 "717764" @default.
- NCIT_C2583 NCIT_P207 "C0795660" @default.
- NCIT_C2583 NCIT_P210 "155141-29-0" @default.
- NCIT_C2583 NCIT_P302 "Non-Insulin-Dependent Diabetes Mellitus and Type II Diabetes Mellitus" @default.
- NCIT_C2583 NCIT_P302 "Type 2 diabetes" @default.
- NCIT_C2583 NCIT_P319 "KX2339DP44" @default.
- NCIT_C2583 NCIT_P322 "CTRP" @default.
- NCIT_C2583 NCIT_P322 "FDA" @default.
- NCIT_C2583 NCIT_P322 "GDC" @default.
- NCIT_C2583 NCIT_P325 "A drug that helps control the amount of glucose (sugar) in the blood and is being studied in the prevention and treatment of some types of cancer. Avandia stops cells from growing and may prevent the growth of new blood vessels that tumors need to grow. It is a type of thiazolidinedione and a type of antiangiogenesis agent." @default.
- NCIT_C2583 NCIT_P329 "37793" @default.
- NCIT_C2583 NCIT_P330 "37793" @default.
- NCIT_C2583 NCIT_P350 "C18H19N3O3S.C4H4O4" @default.
- NCIT_C2583 NCIT_P366 "Rosiglitazone" @default.
- NCIT_C2583 NCIT_P368 "CHEBI:8892" @default.
- NCIT_C2583 NCIT_P375 "Rosiglitazone Maleate" @default.
- NCIT_C2583 NCIT_P399 "37793" @default.
- NCIT_C2583 NCIT_R122 NCIT_C16484 @default.
- NCIT_C2583 NCIT_R122 NCIT_C16486 @default.
- NCIT_C2583 NCIT_R122 NCIT_C16554 @default.
- NCIT_C2583 NCIT_R122 NCIT_C16865 @default.
- NCIT_C2583 NCIT_R122 NCIT_C16946 @default.
- NCIT_C2583 NCIT_R122 NCIT_C17021 @default.
- NCIT_C2583 NCIT_R122 NCIT_C20027 @default.
- NCIT_C2583 NCIT_R122 NCIT_C26548 @default.
- NCIT_C2583 NCIT_R122 NCIT_C28459 @default.
- NCIT_C2583 NCIT_R122 NCIT_C28750 @default.
- NCIT_C2583 normalizedInformationContent "100" @default.
- NCIT_C2583 referenceCount "1" @default.
- NCIT_C2583 hasExactSynonym "(+/-)-5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione, ( Z )-2-Butenedioate (1:1)" @default.
- NCIT_C2583 hasExactSynonym "Avandia" @default.
- NCIT_C2583 hasExactSynonym "BRL49653" @default.
- NCIT_C2583 hasExactSynonym "ROSIGLITAZONE MALEATE" @default.
- NCIT_C2583 hasExactSynonym "Rosiglitazone Maleate" @default.
- NCIT_C2583 hasExactSynonym "rosiglitazone maleate" @default.
- NCIT_C2583 inSubset NCIT_C116977 @default.
- NCIT_C2583 inSubset NCIT_C116978 @default.
- NCIT_C2583 inSubset NCIT_C128784 @default.
- NCIT_C2583 inSubset NCIT_C157711 @default.
- NCIT_C2583 inSubset NCIT_C157712 @default.
- NCIT_C2583 inSubset NCIT_C176424 @default.
- NCIT_C2583 inSubset NCIT_C177537 @default.
- NCIT_C2583 inSubset NCIT_C63923 @default.
- NCIT_C2583 type Class @default.
- NCIT_C2583 isDefinedBy ncit.owl @default.
- NCIT_C2583 label "Rosiglitazone Maleate" @default.
- NCIT_C2583 subClassOf B36601909601ab8dd7ab118fbf427a487 @default.
- NCIT_C2583 subClassOf Bfa8ad16c4057c7d51cee6b63d75c0e3d @default.
- NCIT_C2583 subClassOf NCIT_C1908 @default.
- NCIT_C2583 subClassOf NCIT_C1909 @default.
- NCIT_C2583 subClassOf NCIT_C1934 @default.
- NCIT_C2583 subClassOf NCIT_C2122 @default.
- NCIT_C2583 subClassOf NCIT_C2583 @default.
- NCIT_C2583 subClassOf NCIT_C274 @default.
- NCIT_C2583 subClassOf NCIT_C29711 @default.
- NCIT_C2583 subClassOf NCIT_C78276 @default.
- NCIT_C2583 subClassOf NCIT_C98241 @default.