Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C25842> ?p ?o ?g. }
- NCIT_C25842 IAO_0000115 "Cyclin-dependent kinase 2 (298 aa, ~34 kDa) is encoded by the human CDK2 gene. This protein is involved in the regulation of both phosphorylation of cyclins and the cell cycle progression from the G2 phase to mitosis." @default.
- NCIT_C25842 NCIT_NHC0 "C25842" @default.
- NCIT_C25842 NCIT_P100 "116953" @default.
- NCIT_C25842 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C25842 NCIT_P106 "Enzyme" @default.
- NCIT_C25842 NCIT_P107 "Cyclin-Dependent Kinase 2" @default.
- NCIT_C25842 NCIT_P108 "Cyclin-Dependent Kinase 2" @default.
- NCIT_C25842 NCIT_P207 "C0108855" @default.
- NCIT_C25842 NCIT_P322 "CTRP" @default.
- NCIT_C25842 NCIT_P366 "Cyclin-Dependent_Kinase-2" @default.
- NCIT_C25842 NCIT_P93 "P24941" @default.
- NCIT_C25842 NCIT_P98 "This protein kinase is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. It is involved in promoting DNA synthesis and cell cycle progression. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene exist. Its N-terminal domain interacts with cyclins and C-terminal domain interacts with CSK1. (LocusLink, OMIM)" @default.
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- NCIT_C25842 NCIT_R54 NCIT_C25871 @default.
- NCIT_C25842 NCIT_R54 NCIT_C25872 @default.
- NCIT_C25842 NCIT_R54 NCIT_C25873 @default.
- NCIT_C25842 normalizedInformationContent "100" @default.
- NCIT_C25842 referenceCount "1" @default.
- NCIT_C25842 hasExactSynonym "CDC2-Related Protein Kinase" @default.
- NCIT_C25842 hasExactSynonym "CDK2" @default.
- NCIT_C25842 hasExactSynonym "Cell Division Kinase 2" @default.
- NCIT_C25842 hasExactSynonym "Cell Division Protein Kinase 2" @default.
- NCIT_C25842 hasExactSynonym "Cyclin-Dependent Kinase 2" @default.
- NCIT_C25842 hasExactSynonym "EC 2.7.1.11" @default.
- NCIT_C25842 hasExactSynonym "EC 2.7.11.22" @default.
- NCIT_C25842 hasExactSynonym "p33 Protein Kinase" @default.
- NCIT_C25842 hasExactSynonym "p33(CDK2)" @default.
- NCIT_C25842 inSubset NCIT_C116977 @default.
- NCIT_C25842 inSubset NCIT_C142799 @default.
- NCIT_C25842 inSubset NCIT_C142800 @default.
- NCIT_C25842 type Class @default.
- NCIT_C25842 isDefinedBy ncit.owl @default.