Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C2586> ?p ?o ?g. }
Showing items 1 to 39 of
39
with 100 items per page.
- NCIT_C2586 IAO_0000115 "A furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division. Psoralen is used in Photochemotherapy with high-intensity long-wavelength UVA irradiation. Psoralens are tricyclic furocumarins and have a strong tendency to intercalate with DNA base pairs. Irradiation of nucleic acids in the presence of psoralen with long wave UV (~360 nm) results in the 2+2 cyclo- addition of either of its two photoreactive sites with 5,6-carbon bonds of pyrimidines resulting in crosslinking double-stranded nucleic acids." @default.
- NCIT_C2586 NCIT_NHC0 "C2586" @default.
- NCIT_C2586 NCIT_P106 "Organic Chemical" @default.
- NCIT_C2586 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2586 NCIT_P108 "Psoralen" @default.
- NCIT_C2586 NCIT_P175 "217989" @default.
- NCIT_C2586 NCIT_P207 "C0016072" @default.
- NCIT_C2586 NCIT_P210 "66-97-7" @default.
- NCIT_C2586 NCIT_P302 "Psoriasis; T-cell Lymphoma-Cutaneous; Vitiligo" @default.
- NCIT_C2586 NCIT_P319 "KTZ7ZCN2EX" @default.
- NCIT_C2586 NCIT_P322 "FDA" @default.
- NCIT_C2586 NCIT_P325 "A substance from plants that is sensitive to light (or can be activated by light). Psoralens are used together with UV light to treat psoriasis, vitiligo, and skin nodules of cutaneous T-cell lymphoma. They are also being studied in the treatment of graft-versus-host disease. Psoralen is a type of furocoumarin. An example of a psoralen is methoxsalen." @default.
- NCIT_C2586 NCIT_P329 "37899" @default.
- NCIT_C2586 NCIT_P330 "37899" @default.
- NCIT_C2586 NCIT_P350 "C11H6O3" @default.
- NCIT_C2586 NCIT_P366 "Psoralen" @default.
- NCIT_C2586 NCIT_P368 "CHEBI:27616" @default.
- NCIT_C2586 NCIT_P399 "37899" @default.
- NCIT_C2586 normalizedInformationContent "100" @default.
- NCIT_C2586 referenceCount "1" @default.
- NCIT_C2586 hasExactSynonym "6-hydroxy-5-benzofuranacrylic Acid deta-lacton" @default.
- NCIT_C2586 hasExactSynonym "Ficusin" @default.
- NCIT_C2586 hasExactSynonym "PSORALEN" @default.
- NCIT_C2586 hasExactSynonym "Psoralen" @default.
- NCIT_C2586 hasExactSynonym "psoralen" @default.
- NCIT_C2586 inSubset NCIT_C176424 @default.
- NCIT_C2586 inSubset NCIT_C63923 @default.
- NCIT_C2586 type Class @default.
- NCIT_C2586 isDefinedBy ncit.owl @default.
- NCIT_C2586 label "Psoralen" @default.
- NCIT_C2586 subClassOf NCIT_C186664 @default.
- NCIT_C2586 subClassOf NCIT_C1908 @default.
- NCIT_C2586 subClassOf NCIT_C1909 @default.
- NCIT_C2586 subClassOf NCIT_C2163 @default.
- NCIT_C2586 subClassOf NCIT_C25760 @default.
- NCIT_C2586 subClassOf NCIT_C2586 @default.
- NCIT_C2586 subClassOf NCIT_C274 @default.
- NCIT_C2586 subClassOf NCIT_C2842 @default.
- NCIT_C2586 subClassOf NCIT_C582 @default.