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- NCIT_C2601 IAO_0000115 "A radioconjugate consisting of the octreotide derivative edotreotide labeled with yttrium 90 (Y-90) with potential radiotherapeutic uses. Similar to octreotide, yttrium Y 90-edotreotide binds to somatostatin receptors (SSTRs), especially type 2 receptors, present on the cell membranes of many types of neuroendocrine tumor cells, delivering tissue-specific, beta-emitting nuclide Y-90-mediated cytotoxicity to SSTR-positive cells. Yttrium Y 90-edotreotide is produced by substituting tyrosine for phenylalanine at the 3 position of the somatostatin analogue octreotide and chelating the substituted octreotide to Y-90 via dodecanetetraacetic acid (DOTA)." @default.
- NCIT_C2601 NCIT_A32 NCIT_C1909 @default.
- NCIT_C2601 NCIT_A7 NCIT_C17922 @default.
- NCIT_C2601 NCIT_NHC0 "C2601" @default.
- NCIT_C2601 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2601 NCIT_P107 "Yttrium Y 90-Edotreotide" @default.
- NCIT_C2601 NCIT_P108 "Yttrium Y 90-Edotreotide" @default.
- NCIT_C2601 NCIT_P171 "20168290" @default.
- NCIT_C2601 NCIT_P207 "C2003893" @default.
- NCIT_C2601 NCIT_P210 "322407-70-5" @default.
- NCIT_C2601 NCIT_P319 "ABF7OG3FA3" @default.
- NCIT_C2601 NCIT_P322 "CTRP" @default.
- NCIT_C2601 NCIT_P322 "FDA" @default.
- NCIT_C2601 NCIT_P322 "GDC" @default.
- NCIT_C2601 NCIT_P325 "A substance being studied in the treatment of some types of cancer. Yttrium Y 90 edotreotide contains yttrium Y 90 (a radioactive form of the metal yttrium) attached to a molecule that binds to certain types of neuroendocrine tumors (tumors that come from cells that release hormones). The radioactivity from yttrium Y 90 may kill the cancer cells." @default.
- NCIT_C2601 NCIT_P329 "38102" @default.
- NCIT_C2601 NCIT_P330 "38102" @default.
- NCIT_C2601 NCIT_P366 "Yttrium_Y_90_SMT_487" @default.
- NCIT_C2601 NCIT_P375 "Yttrium Y 90-Edotreotide" @default.
- NCIT_C2601 NCIT_P399 "38102" @default.
- NCIT_C2601 normalizedInformationContent "100" @default.
- NCIT_C2601 referenceCount "1" @default.
- NCIT_C2601 hasExactSynonym "90Y-DOTA-3-Tyr-Octreotide" @default.
- NCIT_C2601 hasExactSynonym "EDOTREOTIDE YTTRIUM Y-90" @default.
- NCIT_C2601 hasExactSynonym "OctreoTher" @default.
- NCIT_C2601 hasExactSynonym "Onalta" @default.
- NCIT_C2601 hasExactSynonym "Yttrium Y 90 -DOTATOC" @default.
- NCIT_C2601 hasExactSynonym "Yttrium Y 90 SMT 487" @default.
- NCIT_C2601 hasExactSynonym "Yttrium Y 90-DOTA-3-tyrosine-octreotide" @default.
- NCIT_C2601 hasExactSynonym "Yttrium Y 90-DOTA-Tyr3-Octreotide" @default.
- NCIT_C2601 hasExactSynonym "Yttrium Y 90-Edotreotide" @default.
- NCIT_C2601 hasExactSynonym "yttrium Y 90 SMT 487" @default.
- NCIT_C2601 hasExactSynonym "yttrium Y 90 edotreotide" @default.
- NCIT_C2601 hasExactSynonym "yttrium Y 90-DOTA-tyr3-octreotide" @default.
- NCIT_C2601 inSubset NCIT_C116977 @default.
- NCIT_C2601 inSubset NCIT_C116978 @default.
- NCIT_C2601 inSubset NCIT_C128784 @default.
- NCIT_C2601 inSubset NCIT_C157711 @default.
- NCIT_C2601 inSubset NCIT_C157712 @default.
- NCIT_C2601 inSubset NCIT_C176424 @default.
- NCIT_C2601 inSubset NCIT_C177537 @default.
- NCIT_C2601 inSubset NCIT_C63923 @default.
- NCIT_C2601 type Class @default.
- NCIT_C2601 isDefinedBy ncit.owl @default.
- NCIT_C2601 label "Yttrium Y 90-Edotreotide" @default.
- NCIT_C2601 subClassOf NCIT_C129819 @default.
- NCIT_C2601 subClassOf NCIT_C1446 @default.
- NCIT_C2601 subClassOf NCIT_C1908 @default.
- NCIT_C2601 subClassOf NCIT_C1909 @default.
- NCIT_C2601 subClassOf NCIT_C2124 @default.
- NCIT_C2601 subClassOf NCIT_C2601 @default.
- NCIT_C2601 subClassOf NCIT_C274 @default.