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Showing items 1 to 100 of ±118 with 100 items per page.

NCIT_C26105 IAO_0000115 "Proteinase-activated receptor 1 (425 aa, ~47 kDa) is encoded by the human F2R gene. This protein plays a role in thrombin-dependent G protein-coupled receptor signaling." @default.
NCIT_C26105 NCIT_NHC0 "C26105" @default.
NCIT_C26105 NCIT_P100 "187930" @default.
NCIT_C26105 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
NCIT_C26105 NCIT_P106 "Receptor" @default.
NCIT_C26105 NCIT_P107 "Protease-Activated Receptor 1" @default.
NCIT_C26105 NCIT_P108 "Protease-Activated Receptor 1" @default.
NCIT_C26105 NCIT_P207 "C0668084" @default.
NCIT_C26105 NCIT_P322 "CTRP" @default.
NCIT_C26105 NCIT_P366 "Coagulation_Factor-II_Receptor" @default.
NCIT_C26105 NCIT_P93 "P25116" @default.
NCIT_C26105 NCIT_P98 "Expressed in platelets and vascular endothelia by human F2R Gene (GPCR1 Family), 425-aa 47-kDa (precursor) Coagulation Factor II Receptor is a 7-transmembrane G-protein coupled high affinity activated thrombin receptor that stimulates phosphoinositide hydrolysis in the cellular thrombotic response. F2R appears to play a role in platelet activation and vascular development. Receptor phosphorylation probably mediates desensitization prior to uncoupling and internalization. Activated protein C uses EPCR as a coreceptor for cleavage of Coagulation Factor II Receptor on endothelia. Proteolytic cleavage of F2R generates a new N-terminus that functions as a tethered ligand." @default.
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NCIT_C26105 hasExactSynonym "Coagulation Factor II Receptor" @default.
NCIT_C26105 hasExactSynonym "F2R" @default.