Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C26149> ?p ?o ?g. }
- NCIT_C26149 IAO_0000115 "B-cell lymphoma 6 protein (706 aa, ~79 kDa) is encoded by the human BCL6 gene. This protein is involved in transcriptional repression, apoptosis regulation and cell cycle progression." @default.
- NCIT_C26149 NCIT_A32 NCIT_C268 @default.
- NCIT_C26149 NCIT_NHC0 "C26149" @default.
- NCIT_C26149 NCIT_P100 "109565" @default.
- NCIT_C26149 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C26149 NCIT_P107 "B-Cell Lymphoma 6 Protein" @default.
- NCIT_C26149 NCIT_P108 "B-Cell Lymphoma 6 Protein" @default.
- NCIT_C26149 NCIT_P207 "C1448774" @default.
- NCIT_C26149 NCIT_P322 "CTRP" @default.
- NCIT_C26149 NCIT_P322 "GDC" @default.
- NCIT_C26149 NCIT_P366 "B-Cell_Lymphoma-6_Protein" @default.
- NCIT_C26149 NCIT_P375 "BCL6" @default.
- NCIT_C26149 NCIT_P93 "P41182" @default.
- NCIT_C26149 NCIT_P98 "B-Cell Lymphoma 6 Protein is a zinc finger transcription factor containing an N-terminal POZ domain. It acts as a sequence-specific repressor of transcription and its activity is dependent upon DNA-binding and on the N-terminal region containing the POZ motif. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. Target genes have roles in B-cell activation, B-cell differentiation, inflammation, and cell cycle control. Expression of BCL6 in some B-cells early in the antigen response may skew them toward a germinal center fate, away from a plasma cell fate. The BCL6 gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. (from OMIM, and LocusLink)" @default.
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