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- NCIT_C2616 IAO_0000115 "A chelated octreotide derivative with somatostatin activity. Edotreotide is produced by substituting tyrosine for phenylalanine at the 3 position of octreotide and chelated via dodecanetetraacetic acid (DOTA). Like octreotide, this edotreotide binds to somatostatin receptors (SSTRs), especially type 2, present on the cell membrane of many types of neuroendocrine tumors. When labeled with nuclides, edotreotide conjugates could result in tissue specific cytotoxicity." @default.
- NCIT_C2616 NCIT_NHC0 "C2616" @default.
- NCIT_C2616 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2616 NCIT_P108 "Edotreotide" @default.
- NCIT_C2616 NCIT_P171 "16917205" @default.
- NCIT_C2616 NCIT_P207 "C0539568" @default.
- NCIT_C2616 NCIT_P210 "204318-14-9" @default.
- NCIT_C2616 NCIT_P319 "U194AS08HZ" @default.
- NCIT_C2616 NCIT_P322 "FDA" @default.
- NCIT_C2616 NCIT_P350 "C65H92N14O18S2" @default.
- NCIT_C2616 NCIT_P366 "SMT-487" @default.
- NCIT_C2616 normalizedInformationContent "100" @default.
- NCIT_C2616 referenceCount "1" @default.
- NCIT_C2616 hasExactSynonym "(DOTA(0)-Phe(1)-Tyr(3))octreotide" @default.
- NCIT_C2616 hasExactSynonym "DOTA-Tyr3-octreotide" @default.
- NCIT_C2616 hasExactSynonym "DOTATOC" @default.
- NCIT_C2616 hasExactSynonym "EDOTREOTIDE" @default.
- NCIT_C2616 hasExactSynonym "Edotreotide" @default.
- NCIT_C2616 hasExactSynonym "L-Cysteinamide, N-((4,7,10-tris(carboxymetnyl)-1,4,7,10-tetraazacyclodec-1-yl)acetyl)-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic(2-7)-disulfide" @default.
- NCIT_C2616 hasExactSynonym "SMT-487" @default.
- NCIT_C2616 inSubset NCIT_C63923 @default.
- NCIT_C2616 type Class @default.
- NCIT_C2616 isDefinedBy ncit.owl @default.
- NCIT_C2616 label "Edotreotide" @default.
- NCIT_C2616 subClassOf NCIT_C147908 @default.
- NCIT_C2616 subClassOf NCIT_C1908 @default.
- NCIT_C2616 subClassOf NCIT_C1909 @default.
- NCIT_C2616 subClassOf NCIT_C2616 @default.
- NCIT_C2616 subClassOf NCIT_C548 @default.
- NCIT_C2616 subClassOf NCIT_C62799 @default.