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- NCIT_C2617 IAO_0000115 "A synthetic sequence of DNA constructed in the antisense orientation to a sequence of DNA in epidermal growth factor receptor (EGFR), a member of the erbB gene family. EGFR antisense DNA suppresses the expression of EGFR by tumor cells, thereby inhibiting tumor cell proliferation and decreasing tumor growth. This agent also appears to reduce the invasiveness of certain breast cancer cells. Members of the erbB gene family are overexpressed in many cancers and play roles in carcinogenesis and the regulation of cell proliferation. (NCI04)" @default.
- NCIT_C2617 NCIT_A7 NCIT_C17068 @default.
- NCIT_C2617 NCIT_NHC0 "C2617" @default.
- NCIT_C2617 NCIT_P106 "Nucleic Acid, Nucleoside, or Nucleotide" @default.
- NCIT_C2617 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2617 NCIT_P107 "EGFR Antisense DNA" @default.
- NCIT_C2617 NCIT_P108 "EGFR Antisense DNA" @default.
- NCIT_C2617 NCIT_P207 "C0935778" @default.
- NCIT_C2617 NCIT_P322 "CTRP" @default.
- NCIT_C2617 NCIT_P329 "38201" @default.
- NCIT_C2617 NCIT_P330 "38201" @default.
- NCIT_C2617 NCIT_P366 "EGFR_Antisense_DNA" @default.
- NCIT_C2617 NCIT_P399 "38201" @default.
- NCIT_C2617 normalizedInformationContent "90.826665450122817" @default.
- NCIT_C2617 referenceCount "4" @default.
- NCIT_C2617 hasExactSynonym "EGFR Antisense DNA" @default.
- NCIT_C2617 inSubset NCIT_C116977 @default.
- NCIT_C2617 inSubset NCIT_C116978 @default.
- NCIT_C2617 inSubset NCIT_C128784 @default.
- NCIT_C2617 inSubset NCIT_C176424 @default.
- NCIT_C2617 type Class @default.
- NCIT_C2617 isDefinedBy ncit.owl @default.
- NCIT_C2617 label "EGFR Antisense DNA" @default.
- NCIT_C2617 subClassOf NCIT_C1291 @default.
- NCIT_C2617 subClassOf NCIT_C129821 @default.
- NCIT_C2617 subClassOf NCIT_C1908 @default.
- NCIT_C2617 subClassOf NCIT_C1909 @default.
- NCIT_C2617 subClassOf NCIT_C1962 @default.
- NCIT_C2617 subClassOf NCIT_C2617 @default.
- NCIT_C2617 subClassOf NCIT_C274 @default.
- NCIT_C2617 subClassOf NCIT_C307 @default.