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- NCIT_C26191 IAO_0000115 "Heterotrimeric G Protein Subunit Genes encode Heterotrimeric G Protein signal transducers, attached to the plasma membrane, that connect seven transmembrane cell surface G-protein coupled receptors to intracellular signal transduction effectors and pathways. Inactive G proteins consist of alpha/beta/gamma complexes that signal as dissociated GTP-bound alpha subunit or the beta/gamma complex. GTP hydrolysis by the inherent GTPase reverts the alpha subunit to its inactive (heterotrimeric) form. Receptors coupled to G proteins communicate signals from hormones, neurotransmitters, chemokines, and autocrine and paracrine factors. (NCI)" @default.
- NCIT_C26191 NCIT_NHC0 "C26191" @default.
- NCIT_C26191 NCIT_P106 "Gene or Genome" @default.
- NCIT_C26191 NCIT_P108 "Heterotrimeric G Protein Subunit Gene" @default.
- NCIT_C26191 NCIT_P207 "C1334000" @default.
- NCIT_C26191 NCIT_P366 "Heterotrimeric_G_Protein_Subunit_Gene" @default.
- NCIT_C26191 NCIT_P96 "Heterotrimeric G Protein" @default.
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- NCIT_C26191 hasExactSynonym "Heterotrimeric G Protein Subunit Gene" @default.
- NCIT_C26191 type Class @default.
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- NCIT_C26191 label "Heterotrimeric G Protein Subunit Gene" @default.
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