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- NCIT_C26253 IAO_0000115 "Cation-independent mannose-6-phosphate receptor (2491 aa, ~274 kDa) is encoded by the human IGF2R gene. This protein is involved in receptor-mediated endocytosis." @default.
- NCIT_C26253 NCIT_NHC0 "C26253" @default.
- NCIT_C26253 NCIT_P100 "147280" @default.
- NCIT_C26253 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C26253 NCIT_P106 "Receptor" @default.
- NCIT_C26253 NCIT_P107 "Cation-Independent Mannose-6 Phosphate Receptor" @default.
- NCIT_C26253 NCIT_P108 "Cation-Independent Mannose-6 Phosphate Receptor" @default.
- NCIT_C26253 NCIT_P207 "C1334189" @default.
- NCIT_C26253 NCIT_P322 "CTRP" @default.
- NCIT_C26253 NCIT_P366 "Insulin-Like_Growth_Factor-2_Receptor" @default.
- NCIT_C26253 NCIT_P93 "P11717" @default.
- NCIT_C26253 NCIT_P98 "IGF2R is a 250kDa transmembrane protein. It was originally identified as a receptor for IGFII and M6P-containing proteins (e.g. lysosomal hydrolases). Lysosomal enzymes are sorted to lysosomes via IGF2R either from the Golgi, where the enzymes acquire M6P, or from the extracellular space. The majority of IGF2R molecules are located intracellularly, only 5-10% is present on the cell membrane. IGF2R is also a receptor for TGFbeta latency associated peptide (LAP), proliferin and may bind several molecules independently of M6P, including plasminogen, CD87 or retinoic acid. It is involved in activation of latent TGFbeta. It is a putative hepatocellular tumor suppressor. (from LocusLink)" @default.
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- NCIT_C26253 NCIT_R53 NCIT_C18992 @default.
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- NCIT_C26253 NCIT_R53 NCIT_C19950 @default.
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- NCIT_C26253 NCIT_R54 NCIT_C21295 @default.
- NCIT_C26253 NCIT_R54 NCIT_C24487 @default.
- NCIT_C26253 NCIT_R54 NCIT_C26131 @default.
- NCIT_C26253 normalizedInformationContent "100" @default.
- NCIT_C26253 referenceCount "1" @default.
- NCIT_C26253 hasExactSynonym "300 kDa Mannose 6-Phosphate Receptor" @default.
- NCIT_C26253 hasExactSynonym "Antigen CD222" @default.
- NCIT_C26253 hasExactSynonym "CD222 Antigen" @default.
- NCIT_C26253 hasExactSynonym "CD222" @default.
- NCIT_C26253 hasExactSynonym "CI Man-6-P Receptor" @default.
- NCIT_C26253 hasExactSynonym "CI-MPR" @default.
- NCIT_C26253 hasExactSynonym "Cation-Independent Mannose-6 Phosphate Receptor" @default.
- NCIT_C26253 hasExactSynonym "IGF-II Receptor" @default.
- NCIT_C26253 hasExactSynonym "IGF2R" @default.
- NCIT_C26253 hasExactSynonym "Insulin-Like Growth Factor 2 Receptor" @default.
- NCIT_C26253 hasExactSynonym "Insulin-Like Growth Factor II Receptor" @default.
- NCIT_C26253 hasExactSynonym "M6P/IGF2 Receptor" @default.
- NCIT_C26253 hasExactSynonym "M6P/IGF2R" @default.
- NCIT_C26253 hasExactSynonym "M6PR" @default.
- NCIT_C26253 hasExactSynonym "MPR 300" @default.
- NCIT_C26253 inSubset NCIT_C116977 @default.
- NCIT_C26253 inSubset NCIT_C142799 @default.
- NCIT_C26253 inSubset NCIT_C142800 @default.
- NCIT_C26253 type Class @default.
- NCIT_C26253 isDefinedBy ncit.owl @default.
- NCIT_C26253 label "Cation-Independent Mannose-6 Phosphate Receptor" @default.
- NCIT_C26253 subClassOf NCIT_C17021 @default.
- NCIT_C26253 subClassOf NCIT_C17530 @default.
- NCIT_C26253 subClassOf NCIT_C17664 @default.
- NCIT_C26253 subClassOf NCIT_C17728 @default.
- NCIT_C26253 subClassOf NCIT_C18106 @default.
- NCIT_C26253 subClassOf NCIT_C20027 @default.
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- NCIT_C26253 subClassOf NCIT_C26548 @default.
- NCIT_C26253 equivalentClass B4799ba81da5d0550fe21b24efb6e7778 @default.
- NCIT_C26253 equivalentClass Bc666c661fb3da6b59b9cb6099cbe9451 @default.