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- NCIT_C2635 IAO_0000115 "An orally active synthetic antifibrotic agent structurally similar to pyridine 2,4-dicarboxylate. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors, thereby slowing tumor cell proliferation. This agent also inhibits DNA synthesis and the production of mRNA for collagen types I and III, resulting in a reduction in radiation-induced fibrosis. (NCI04)" @default.
- NCIT_C2635 NCIT_A32 NCIT_C1909 @default.
- NCIT_C2635 NCIT_NHC0 "C2635" @default.
- NCIT_C2635 NCIT_P106 "Organic Chemical" @default.
- NCIT_C2635 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2635 NCIT_P108 "Pirfenidone" @default.
- NCIT_C2635 NCIT_P207 "C0298067" @default.
- NCIT_C2635 NCIT_P210 "53179-13-8" @default.
- NCIT_C2635 NCIT_P319 "D7NLD2JX7U" @default.
- NCIT_C2635 NCIT_P322 "FDA" @default.
- NCIT_C2635 NCIT_P322 "GDC" @default.
- NCIT_C2635 NCIT_P325 "A substance that is being studied in the prevention and treatment of scar tissue caused by radiation therapy. It belongs to the family of drugs called anti-inflammatory agents." @default.
- NCIT_C2635 NCIT_P329 "38334" @default.
- NCIT_C2635 NCIT_P330 "38334" @default.
- NCIT_C2635 NCIT_P350 "C12H11NO" @default.
- NCIT_C2635 NCIT_P366 "Pirfenidone" @default.
- NCIT_C2635 NCIT_P375 "Pirfenidone" @default.
- NCIT_C2635 NCIT_P399 "38334" @default.
- NCIT_C2635 normalizedInformationContent "100" @default.
- NCIT_C2635 referenceCount "1" @default.
- NCIT_C2635 hasExactSynonym "PIRFENIDONE" @default.
- NCIT_C2635 hasExactSynonym "Pirfenidone" @default.
- NCIT_C2635 hasExactSynonym "pirfenidone" @default.
- NCIT_C2635 inSubset NCIT_C128784 @default.
- NCIT_C2635 inSubset NCIT_C157711 @default.
- NCIT_C2635 inSubset NCIT_C157712 @default.
- NCIT_C2635 inSubset NCIT_C173381 @default.
- NCIT_C2635 inSubset NCIT_C173383 @default.
- NCIT_C2635 inSubset NCIT_C176424 @default.
- NCIT_C2635 inSubset NCIT_C177537 @default.
- NCIT_C2635 inSubset NCIT_C63923 @default.
- NCIT_C2635 type Class @default.
- NCIT_C2635 isDefinedBy ncit.owl @default.
- NCIT_C2635 label "Pirfenidone" @default.
- NCIT_C2635 subClassOf NCIT_C1908 @default.
- NCIT_C2635 subClassOf NCIT_C1909 @default.
- NCIT_C2635 subClassOf NCIT_C2198 @default.
- NCIT_C2635 subClassOf NCIT_C2356 @default.
- NCIT_C2635 subClassOf NCIT_C241 @default.
- NCIT_C2635 subClassOf NCIT_C257 @default.
- NCIT_C2635 subClassOf NCIT_C26170 @default.
- NCIT_C2635 subClassOf NCIT_C2635 @default.
- NCIT_C2635 subClassOf NCIT_C78272 @default.
- NCIT_C2635 subClassOf NCIT_C797 @default.