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- NCIT_C2637 IAO_0000115 "A chimeric peptide immunogen of human epidermal growth factor-2 (HER-2) with antineoplastic property. HER-2 protein is a receptor tyrosine kinase and a tumor-associated antigen (TAA) that is overexpressed in a variety of cancers. MVF-HER-2(628-647)-CRL 1005 vaccine, coated with poloxamer CRL-1005 to form microparticles, consists of a mutated HER-2 B-cell epitope, HER-2(628-647), and a promiscuous T cell epitope (amino acid sequence 288-302) of the measles virus fusion protein (MVF). Vaccination with this immunogen may stimulate the host immune response to mount a cytotoxic T-lymphocyte response against tumor cells that overexpress the HER2 protein, resulting in tumor cell lysis." @default.
- NCIT_C2637 NCIT_NHC0 "C2637" @default.
- NCIT_C2637 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C2637 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2637 NCIT_P108 "MVF-HER-2(628-647)-CRL 1005 Vaccine" @default.
- NCIT_C2637 NCIT_P171 "10919651" @default.
- NCIT_C2637 NCIT_P207 "C0935910" @default.
- NCIT_C2637 NCIT_P329 "38336" @default.
- NCIT_C2637 NCIT_P330 "38336" @default.
- NCIT_C2637 NCIT_P366 "MVF-HER-2_628-647-CRL_1005_Vaccine" @default.
- NCIT_C2637 NCIT_P399 "38336" @default.
- NCIT_C2637 normalizedInformationContent "100" @default.
- NCIT_C2637 referenceCount "1" @default.
- NCIT_C2637 hasExactSynonym "MVF-HER-2(628-647)-CRL 1005 Vaccine" @default.
- NCIT_C2637 inSubset NCIT_C128784 @default.
- NCIT_C2637 inSubset NCIT_C176424 @default.
- NCIT_C2637 type Class @default.
- NCIT_C2637 isDefinedBy ncit.owl @default.
- NCIT_C2637 label "MVF-HER-2(628-647)-CRL 1005 Vaccine" @default.
- NCIT_C2637 subClassOf NCIT_C129820 @default.
- NCIT_C2637 subClassOf NCIT_C1663 @default.
- NCIT_C2637 subClassOf NCIT_C1908 @default.
- NCIT_C2637 subClassOf NCIT_C1909 @default.
- NCIT_C2637 subClassOf NCIT_C2637 @default.
- NCIT_C2637 subClassOf NCIT_C274 @default.
- NCIT_C2637 subClassOf NCIT_C307 @default.
- NCIT_C2637 subClassOf NCIT_C308 @default.
- NCIT_C2637 subClassOf NCIT_C923 @default.