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- NCIT_C26447 IAO_0000115 "A chimeric IgG1 monoclonal antibody directed against CD80, the natural ligand for the T-cell antigen CD28 which mediates T-cell and B-cell adhesion. Galiximab binds to CD80 expressed on the cell surfaces of follicular lymphomas, resulting in antibody-dependent cell-mediated cytotoxicity (ADCC). CD80 is expressed on activated B-cells and gamma-interferon-stimulated monocytes and is often expressed at low levels on the surfaces of follicular lymphoma cells and other lymphoid malignancies." @default.
- NCIT_C26447 NCIT_A32 NCIT_C1909 @default.
- NCIT_C26447 NCIT_A7 NCIT_C15173 @default.
- NCIT_C26447 NCIT_NHC0 "C26447" @default.
- NCIT_C26447 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C26447 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C26447 NCIT_P107 "Galiximab" @default.
- NCIT_C26447 NCIT_P108 "Galiximab" @default.
- NCIT_C26447 NCIT_P175 "734532" @default.
- NCIT_C26447 NCIT_P207 "C1098262" @default.
- NCIT_C26447 NCIT_P210 "357613-77-5" @default.
- NCIT_C26447 NCIT_P319 "S9OX9692ZB" @default.
- NCIT_C26447 NCIT_P322 "CTRP" @default.
- NCIT_C26447 NCIT_P322 "FDA" @default.
- NCIT_C26447 NCIT_P322 "GDC" @default.
- NCIT_C26447 NCIT_P325 "A substance being studied in the treatment of follicular non-Hodgkin lymphoma. It binds to the protein CD80, which is found on certain normal white blood cells and on white blood cells that are cancer. It is a type of monoclonal antibody." @default.
- NCIT_C26447 NCIT_P329 "285686" @default.
- NCIT_C26447 NCIT_P330 "285686" @default.
- NCIT_C26447 NCIT_P366 "IDEC-114_Monoclonal_Antibody" @default.
- NCIT_C26447 NCIT_P375 "Galiximab" @default.
- NCIT_C26447 NCIT_P399 "285686" @default.
- NCIT_C26447 NCIT_R124 NCIT_C17710 @default.
- NCIT_C26447 NCIT_R124 NCIT_C17828 @default.
- NCIT_C26447 NCIT_R124 NCIT_C18219 @default.
- NCIT_C26447 NCIT_R124 NCIT_C19986 @default.
- NCIT_C26447 NCIT_R124 NCIT_C40474 @default.
- NCIT_C26447 normalizedInformationContent "95.413332725061409" @default.
- NCIT_C26447 referenceCount "2" @default.
- NCIT_C26447 hasExactSynonym "GALIXIMAB" @default.
- NCIT_C26447 hasExactSynonym "Galiximab" @default.
- NCIT_C26447 hasExactSynonym "IDEC-114" @default.
- NCIT_C26447 hasExactSynonym "anti-B7-1" @default.
- NCIT_C26447 hasExactSynonym "anti-CD80 Antibody" @default.
- NCIT_C26447 hasExactSynonym "galiximab" @default.
- NCIT_C26447 inSubset NCIT_C116977 @default.
- NCIT_C26447 inSubset NCIT_C116978 @default.
- NCIT_C26447 inSubset NCIT_C128784 @default.
- NCIT_C26447 inSubset NCIT_C157711 @default.
- NCIT_C26447 inSubset NCIT_C157712 @default.
- NCIT_C26447 inSubset NCIT_C176424 @default.
- NCIT_C26447 inSubset NCIT_C177537 @default.
- NCIT_C26447 inSubset NCIT_C63923 @default.
- NCIT_C26447 type Class @default.
- NCIT_C26447 isDefinedBy ncit.owl @default.
- NCIT_C26447 label "Galiximab" @default.
- NCIT_C26447 subClassOf NCIT_C1908 @default.
- NCIT_C26447 subClassOf NCIT_C1909 @default.
- NCIT_C26447 subClassOf NCIT_C20401 @default.
- NCIT_C26447 subClassOf NCIT_C26447 @default.
- NCIT_C26447 subClassOf NCIT_C307 @default.
- NCIT_C26447 subClassOf NCIT_C308 @default.