Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C26480> ?p ?o ?g. }
- NCIT_C26480 IAO_0000115 "Mothers against decapentaplegic homolog 2 (467 aa, ~52 kDa) is encoded by the human SMAD2 gene. This protein plays a role in signal transduction and transcriptional regulation." @default.
- NCIT_C26480 NCIT_NHC0 "C26480" @default.
- NCIT_C26480 NCIT_P100 "601366" @default.
- NCIT_C26480 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C26480 NCIT_P107 "Mothers Against Decapentaplegic Homolog 2" @default.
- NCIT_C26480 NCIT_P108 "Mothers Against Decapentaplegic Homolog 2" @default.
- NCIT_C26480 NCIT_P207 "C1566790" @default.
- NCIT_C26480 NCIT_P322 "CTRP" @default.
- NCIT_C26480 NCIT_P366 "SMAD2_Protein" @default.
- NCIT_C26480 NCIT_P93 "Q15796" @default.
- NCIT_C26480 NCIT_P98 "Retained by cytoplasmic SARA, SMAD2/SMAD3 are phosphorylated on conserved C-terminal MH2 docking SER-X-SERs by activated receptor. SMAD2/SMAD3 oligomerize with nuclear SMAD4, disrupting SNON/SMAD4 repressors. SMAD3 causes SNON degradation. SMAD2/SMAD4 activate target promoters. TGFBR activity maintains nuclear SMADs and increases feedback SNON expression. SMAD2 interacts with FAST-1/-2, TGIF, PEBP2-A, CBP, p300, c-SKI, NUP214, NUP153, and SMURF2. MADR2 mutations may disrupt growth inhibition. (from LocusLink, Swiss-Prot, OMIM)" @default.
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- NCIT_C26480 normalizedInformationContent "100" @default.
- NCIT_C26480 referenceCount "1" @default.
- NCIT_C26480 hasExactSynonym "JV18-1" @default.
- NCIT_C26480 hasExactSynonym "MAD (Mothers Against Decapentaplegic, Drosophila) Homolog 2 Protein" @default.
- NCIT_C26480 hasExactSynonym "MAD Homolog 2" @default.
- NCIT_C26480 hasExactSynonym "MAD, Mothers Against Decapentaplegic Homolog 2 Protein" @default.
- NCIT_C26480 hasExactSynonym "MAD-Related Protein 2" @default.
- NCIT_C26480 hasExactSynonym "MADH2" @default.
- NCIT_C26480 hasExactSynonym "Mad-Related Protein 2" @default.
- NCIT_C26480 hasExactSynonym "Mothers Against DPP Homolog 2 Protein" @default.
- NCIT_C26480 hasExactSynonym "Mothers Against DPP Homolog 2" @default.
- NCIT_C26480 hasExactSynonym "Mothers Against Decapentaplegic Homolog 2 Protein" @default.
- NCIT_C26480 hasExactSynonym "Mothers Against Decapentaplegic Homolog 2" @default.
- NCIT_C26480 hasExactSynonym "Mothers Against Decapentaplegic, Drosophila, Homolog 2 Protein" @default.
- NCIT_C26480 hasExactSynonym "SMA- and MAD-Related Protein 2" @default.
- NCIT_C26480 hasExactSynonym "SMAD Family Member 2" @default.
- NCIT_C26480 hasExactSynonym "SMAD2 Protein" @default.
- NCIT_C26480 hasExactSynonym "SMAD2" @default.
- NCIT_C26480 hasExactSynonym "Smad2" @default.
- NCIT_C26480 hasExactSynonym "hMAD-2" @default.
- NCIT_C26480 hasExactSynonym "hSMAD2" @default.
- NCIT_C26480 inSubset NCIT_C116977 @default.