Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C26638> ?p ?o ?g. }
Showing items 1 to 58 of
58
with 100 items per page.
- NCIT_C26638 IAO_0000115 "A second generation purine nucleoside analog with antineoplastic activity. Clofarabine is phosphorylated intracellularly to the cytotoxic active 5'-triphosphate metabolite, which inhibits the enzymatic activities of ribonucleotide reductase and DNA polymerase, resulting in inhibition of DNA repair and synthesis of DNA and RNA. This nucleoside analog also disrupts mitochondrial function and membrane integrity, resulting in the release of pre-apoptotic factors, including cytochrome C and apoptotic-inducing factors, which activate apoptosis." @default.
- NCIT_C26638 NCIT_A24 NCIT_C274 @default.
- NCIT_C26638 NCIT_A32 NCIT_C1909 @default.
- NCIT_C26638 NCIT_A7 NCIT_C17101 @default.
- NCIT_C26638 NCIT_A7 NCIT_C19172 @default.
- NCIT_C26638 NCIT_NHC0 "C26638" @default.
- NCIT_C26638 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C26638 NCIT_P107 "Clofarabine" @default.
- NCIT_C26638 NCIT_P108 "Clofarabine" @default.
- NCIT_C26638 NCIT_P175 "606869" @default.
- NCIT_C26638 NCIT_P207 "C0092777" @default.
- NCIT_C26638 NCIT_P210 "123318-82-1" @default.
- NCIT_C26638 NCIT_P302 "Acute lymphoblastic leukemia, pediatric" @default.
- NCIT_C26638 NCIT_P319 "762RDY0Y2H" @default.
- NCIT_C26638 NCIT_P322 "CTRP" @default.
- NCIT_C26638 NCIT_P322 "FDA" @default.
- NCIT_C26638 NCIT_P322 "GDC" @default.
- NCIT_C26638 NCIT_P322 "PCDC" @default.
- NCIT_C26638 NCIT_P325 "A drug used to treat certain types of acute lymphoblastic leukemia in children. It is also being studied in the treatment of other types of cancer. Clolar is a type of nucleoside analog." @default.
- NCIT_C26638 NCIT_P329 "257309" @default.
- NCIT_C26638 NCIT_P330 "257309" @default.
- NCIT_C26638 NCIT_P350 "C10H11ClFN5O3" @default.
- NCIT_C26638 NCIT_P366 "Clofarabine" @default.
- NCIT_C26638 NCIT_P368 "CHEBI:47311" @default.
- NCIT_C26638 NCIT_P368 "CHEBI:681569" @default.
- NCIT_C26638 NCIT_P375 "Clofarabine" @default.
- NCIT_C26638 NCIT_P399 "257309" @default.
- NCIT_C26638 normalizedInformationContent "87.123597049860606" @default.
- NCIT_C26638 referenceCount "7" @default.
- NCIT_C26638 hasExactSynonym "2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-6-amine" @default.
- NCIT_C26638 hasExactSynonym "2-Chloro-9-(2-deoxy-2-fluoroarabinofuranosyl)adenine" @default.
- NCIT_C26638 hasExactSynonym "CLOFARABINE" @default.
- NCIT_C26638 hasExactSynonym "Clofarabine" @default.
- NCIT_C26638 hasExactSynonym "Clofarex" @default.
- NCIT_C26638 hasExactSynonym "Clolar" @default.
- NCIT_C26638 hasExactSynonym "clofarabine" @default.
- NCIT_C26638 inSubset NCIT_C116977 @default.
- NCIT_C26638 inSubset NCIT_C116978 @default.
- NCIT_C26638 inSubset NCIT_C128784 @default.
- NCIT_C26638 inSubset NCIT_C157711 @default.
- NCIT_C26638 inSubset NCIT_C157712 @default.
- NCIT_C26638 inSubset NCIT_C173234 @default.
- NCIT_C26638 inSubset NCIT_C174019 @default.
- NCIT_C26638 inSubset NCIT_C176424 @default.
- NCIT_C26638 inSubset NCIT_C177537 @default.
- NCIT_C26638 inSubset NCIT_C63923 @default.
- NCIT_C26638 type Class @default.
- NCIT_C26638 isDefinedBy ncit.owl @default.
- NCIT_C26638 label "Clofarabine" @default.
- NCIT_C26638 subClassOf NCIT_C1556 @default.
- NCIT_C26638 subClassOf NCIT_C186664 @default.
- NCIT_C26638 subClassOf NCIT_C1908 @default.
- NCIT_C26638 subClassOf NCIT_C1909 @default.
- NCIT_C26638 subClassOf NCIT_C2150 @default.
- NCIT_C26638 subClassOf NCIT_C26638 @default.
- NCIT_C26638 subClassOf NCIT_C272 @default.
- NCIT_C26638 subClassOf NCIT_C274 @default.
- NCIT_C26638 subClassOf NCIT_C471 @default.