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- NCIT_C26644 IAO_0000115 "The mesylate salt of a synthetic analogue of halichondrin B, a substance derived from a marine sponge (Lissodendoryx sp.) with antineoplastic activity. Eribulin binds to the vinca domain of tubulin and inhibits the polymerization of tubulin and the assembly of microtubules, resulting in inhibition of mitotic spindle assembly, induction of cell cycle arrest at G2/M phase, and, potentially, tumor regression." @default.
- NCIT_C26644 NCIT_A32 NCIT_C1909 @default.
- NCIT_C26644 NCIT_A6 NCIT_C96748 @default.
- NCIT_C26644 NCIT_A7 NCIT_C17219 @default.
- NCIT_C26644 NCIT_NHC0 "C26644" @default.
- NCIT_C26644 NCIT_P106 "Organic Chemical" @default.
- NCIT_C26644 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C26644 NCIT_P107 "Eribulin Mesylate" @default.
- NCIT_C26644 NCIT_P108 "Eribulin Mesylate" @default.
- NCIT_C26644 NCIT_P175 "707389" @default.
- NCIT_C26644 NCIT_P207 "C2608038" @default.
- NCIT_C26644 NCIT_P210 "253128-41-5" @default.
- NCIT_C26644 NCIT_P302 "unresectable or metastatic liposarcoma; breast cancer" @default.
- NCIT_C26644 NCIT_P319 "AV9U0660CW" @default.
- NCIT_C26644 NCIT_P322 "CTRP" @default.
- NCIT_C26644 NCIT_P322 "FDA" @default.
- NCIT_C26644 NCIT_P322 "GDC" @default.
- NCIT_C26644 NCIT_P325 "A drug used to treat metastatic breast cancer in patients who have already been treated with other chemotherapy. It is also being studied in the treatment of other types of cancer. Halaven may block cancer cell growth by stopping cell division. It belongs to the family of drugs called antitubulin agents." @default.
- NCIT_C26644 NCIT_P329 "257773" @default.
- NCIT_C26644 NCIT_P330 "257773" @default.
- NCIT_C26644 NCIT_P350 "C40H59NO11.CH4O3S" @default.
- NCIT_C26644 NCIT_P366 "E7389" @default.
- NCIT_C26644 NCIT_P375 "Eribulin Mesylate" @default.
- NCIT_C26644 NCIT_P399 "257773" @default.
- NCIT_C26644 NCIT_R124 NCIT_C17828 @default.
- NCIT_C26644 NCIT_R124 NCIT_C20480 @default.
- NCIT_C26644 NCIT_R124 NCIT_C40795 @default.
- NCIT_C26644 NCIT_R124 NCIT_C40798 @default.
- NCIT_C26644 NCIT_R125 NCIT_C16397 @default.
- NCIT_C26644 NCIT_R125 NCIT_C17828 @default.
- NCIT_C26644 NCIT_R125 NCIT_C18824 @default.
- NCIT_C26644 NCIT_R125 NCIT_C20150 @default.
- NCIT_C26644 NCIT_R125 NCIT_C20480 @default.
- NCIT_C26644 NCIT_R125 NCIT_C21102 @default.
- NCIT_C26644 NCIT_R125 NCIT_C40715 @default.
- NCIT_C26644 NCIT_R125 NCIT_C41515 @default.
- NCIT_C26644 NCIT_R125 NCIT_C51037 @default.
- NCIT_C26644 NCIT_R146 NCIT_C16492 @default.
- NCIT_C26644 NCIT_R146 NCIT_C17021 @default.
- NCIT_C26644 NCIT_R146 NCIT_C17219 @default.
- NCIT_C26644 NCIT_R146 NCIT_C18073 @default.
- NCIT_C26644 NCIT_R146 NCIT_C20027 @default.
- NCIT_C26644 NCIT_R146 NCIT_C26548 @default.
- NCIT_C26644 normalizedInformationContent "90.826665450122817" @default.
- NCIT_C26644 referenceCount "4" @default.
- NCIT_C26644 hasExactSynonym "2-(3-Amino-2-hydroxypropyl)hexacosahydro-3-methoxy-26-methyl-20,27-bis(methylene)11,15-18,21-24,28-triepoxy-7,9-ethano-12,15-methano-9H,15H-furo(3,2-i)furo(2',3'-5,6)pyrano(4,3-b)(1,4)dioxacyclopentacosin-5-(4H)-one" @default.
- NCIT_C26644 hasExactSynonym "B1939 Mesylate" @default.
- NCIT_C26644 hasExactSynonym "E7389" @default.
- NCIT_C26644 hasExactSynonym "ER-086526 Mesylate" @default.
- NCIT_C26644 hasExactSynonym "ERIBULIN MESYLATE" @default.
- NCIT_C26644 hasExactSynonym "Eribulin Mesylate" @default.
- NCIT_C26644 hasExactSynonym "Halaven" @default.
- NCIT_C26644 hasExactSynonym "Halichondrin B Analog" @default.
- NCIT_C26644 hasExactSynonym "eribulin mesylate" @default.
- NCIT_C26644 inSubset NCIT_C116977 @default.
- NCIT_C26644 inSubset NCIT_C116978 @default.
- NCIT_C26644 inSubset NCIT_C128784 @default.
- NCIT_C26644 inSubset NCIT_C157711 @default.
- NCIT_C26644 inSubset NCIT_C157712 @default.
- NCIT_C26644 inSubset NCIT_C176424 @default.
- NCIT_C26644 inSubset NCIT_C177537 @default.
- NCIT_C26644 inSubset NCIT_C63923 @default.
- NCIT_C26644 type Class @default.
- NCIT_C26644 isDefinedBy ncit.owl @default.
- NCIT_C26644 label "Eribulin Mesylate" @default.
- NCIT_C26644 subClassOf B18b3f76ae396b9ac999828e03094e453 @default.
- NCIT_C26644 subClassOf B1ba309af7ee7d960a3d7afec48933987 @default.
- NCIT_C26644 subClassOf B206455150b0920eaddc041c635a8a6d1 @default.
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- NCIT_C26644 subClassOf B70135fd292f9218f0a42746d2cd61ee2 @default.
- NCIT_C26644 subClassOf B8f57d2269f9aa177e1aa8136a1840661 @default.
- NCIT_C26644 subClassOf B9c043b0e8ae2d4aad2ecd8e23b221084 @default.
- NCIT_C26644 subClassOf Be2b9e047716378c1cb0347bff9a59f1d @default.
- NCIT_C26644 subClassOf NCIT_C186664 @default.
- NCIT_C26644 subClassOf NCIT_C1908 @default.
- NCIT_C26644 subClassOf NCIT_C1909 @default.
- NCIT_C26644 subClassOf NCIT_C25974 @default.
- NCIT_C26644 subClassOf NCIT_C26644 @default.
- NCIT_C26644 subClassOf NCIT_C273 @default.
- NCIT_C26644 subClassOf NCIT_C274 @default.
- NCIT_C26644 subClassOf NCIT_C67422 @default.