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- NCIT_C26680 IAO_0000115 "A tumor-associated antigen belonging to the family of immunogenic testicular proteins that are aberrantly expressed in human cancers in a lineage-nonspecific fashion. Reverse transcription-PCR analysis showed NY-ESO-1 mRNA expression in a variable proportion of a wide array of human cancers, including melanoma, breast cancer, bladder cancer, prostate cancer, and hepatocellular carcinoma; and restricted expression in normal tissues, with high-level mRNA expression found only in testis and ovary tissues. The gene for NY-ESO-1 maps to Xq28 and codes for an 18-kDa protein having no homology with any known protein. NY-ESO-1 elicits a strong, integrated humoral and cellular immune response in a high proportion of patients with NY-ESO-1-expressing tumors and is under investigation as a cancer immunotherapy agent." @default.
- NCIT_C26680 NCIT_A32 NCIT_C1909 @default.
- NCIT_C26680 NCIT_NHC0 "C26680" @default.
- NCIT_C26680 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C26680 NCIT_P108 "NY-ESO-B" @default.
- NCIT_C26680 NCIT_P207 "C1327762" @default.
- NCIT_C26680 NCIT_P322 "GDC" @default.
- NCIT_C26680 NCIT_P329 "257347" @default.
- NCIT_C26680 NCIT_P330 "257347" @default.
- NCIT_C26680 NCIT_P366 "NY-ESO-B" @default.
- NCIT_C26680 NCIT_P375 "NY-ESO-B" @default.
- NCIT_C26680 NCIT_P399 "257347" @default.
- NCIT_C26680 NCIT_R124 NCIT_C17828 @default.
- NCIT_C26680 NCIT_R124 NCIT_C17930 @default.
- NCIT_C26680 NCIT_R124 NCIT_C17937 @default.
- NCIT_C26680 NCIT_R124 NCIT_C18839 @default.
- NCIT_C26680 NCIT_R124 NCIT_C21124 @default.
- NCIT_C26680 NCIT_R124 NCIT_C45548 @default.
- NCIT_C26680 normalizedInformationContent "89.350088392419622" @default.
- NCIT_C26680 referenceCount "5" @default.
- NCIT_C26680 hasExactSynonym "NY-ESO-B" @default.
- NCIT_C26680 inSubset NCIT_C128784 @default.
- NCIT_C26680 inSubset NCIT_C157711 @default.
- NCIT_C26680 inSubset NCIT_C157712 @default.
- NCIT_C26680 inSubset NCIT_C176424 @default.
- NCIT_C26680 inSubset NCIT_C177537 @default.
- NCIT_C26680 type Class @default.
- NCIT_C26680 isDefinedBy ncit.owl @default.
- NCIT_C26680 label "NY-ESO-B" @default.
- NCIT_C26680 subClassOf NCIT_C129820 @default.
- NCIT_C26680 subClassOf NCIT_C1663 @default.
- NCIT_C26680 subClassOf NCIT_C1752 @default.
- NCIT_C26680 subClassOf NCIT_C1908 @default.
- NCIT_C26680 subClassOf NCIT_C1909 @default.
- NCIT_C26680 subClassOf NCIT_C2517 @default.
- NCIT_C26680 subClassOf NCIT_C26680 @default.
- NCIT_C26680 subClassOf NCIT_C274 @default.
- NCIT_C26680 subClassOf NCIT_C307 @default.
- NCIT_C26680 subClassOf NCIT_C308 @default.
- NCIT_C26680 subClassOf NCIT_C923 @default.