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- NCIT_C2678 IAO_0000115 "A polysaccharide isolated from the cell walls of bacteria, plants, and fungi with immunostimulant and antineoplastic activities. In a solubilized form, beta-glucan binds to a lectin site within complement receptor 3 (CR3) on leukocytes, priming the receptor to trigger cytotoxic degranulation of leukocytes when leukocyte CR3 binds to complement 3 (iC3b)-coated tumors. Thus, the attachment of beta-glucan to CR3 of circulating leukocytes simulates leukocytes to kill iC3b-coated tumor cells in the same way as they kill iC3b-coated yeast. (NCI04)" @default.
- NCIT_C2678 NCIT_A32 NCIT_C1909 @default.
- NCIT_C2678 NCIT_NHC0 "C2678" @default.
- NCIT_C2678 NCIT_P106 "Organic Chemical" @default.
- NCIT_C2678 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2678 NCIT_P107 "Beta-Glucan" @default.
- NCIT_C2678 NCIT_P108 "Beta-Glucan" @default.
- NCIT_C2678 NCIT_P207 "C1134651" @default.
- NCIT_C2678 NCIT_P322 "CTRP" @default.
- NCIT_C2678 NCIT_P322 "GDC" @default.
- NCIT_C2678 NCIT_P325 "A substance found in bacteria, plants, and certain foods, such as baker's yeast, cereal grains, and mushrooms. It is a type of polysaccharide that is made of a string of glucose (sugar) molecules joined together. Beta-glucan may stimulate the immune system and help kill cancer cells. It is being studied in the treatment of cancer. It is a type of biological response modifier." @default.
- NCIT_C2678 NCIT_P329 "38642" @default.
- NCIT_C2678 NCIT_P330 "38642" @default.
- NCIT_C2678 NCIT_P366 "Beta-Glucan" @default.
- NCIT_C2678 NCIT_P368 "CHEBI:28793" @default.
- NCIT_C2678 NCIT_P375 "Beta-Glucan" @default.
- NCIT_C2678 NCIT_P399 "38642" @default.
- NCIT_C2678 normalizedInformationContent "95.413332725061409" @default.
- NCIT_C2678 referenceCount "2" @default.
- NCIT_C2678 hasExactSynonym "Beta-Glucan" @default.
- NCIT_C2678 hasExactSynonym "beta-glucan" @default.
- NCIT_C2678 inSubset NCIT_C116977 @default.
- NCIT_C2678 inSubset NCIT_C116978 @default.
- NCIT_C2678 inSubset NCIT_C128784 @default.
- NCIT_C2678 inSubset NCIT_C157711 @default.
- NCIT_C2678 inSubset NCIT_C157712 @default.
- NCIT_C2678 inSubset NCIT_C176424 @default.
- NCIT_C2678 inSubset NCIT_C177537 @default.
- NCIT_C2678 type Class @default.
- NCIT_C2678 isDefinedBy ncit.owl @default.
- NCIT_C2678 label "Beta-Glucan" @default.
- NCIT_C2678 subClassOf NCIT_C1908 @default.
- NCIT_C2678 subClassOf NCIT_C1909 @default.
- NCIT_C2678 subClassOf NCIT_C2139 @default.
- NCIT_C2678 subClassOf NCIT_C2678 @default.
- NCIT_C2678 subClassOf NCIT_C308 @default.