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- NCIT_C2679 IAO_0000115 "An orally bioavailable antimitotic sulfonamide. ABT- 751 binds to the colchicine-binding site on beta-tubulin and inhibits the polymerization of microtubules, thereby preventing tumor cell replication. This agent also disrupts tumor neovascularization, reducing tumor blood flow and so inducing a cytotoxic effect. (NCI04)" @default.
- NCIT_C2679 NCIT_A32 NCIT_C1909 @default.
- NCIT_C2679 NCIT_A7 NCIT_C129655 @default.
- NCIT_C2679 NCIT_NHC0 "C2679" @default.
- NCIT_C2679 NCIT_P106 "Organic Chemical" @default.
- NCIT_C2679 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2679 NCIT_P107 "Colchicine-Site Binding Agent ABT-751" @default.
- NCIT_C2679 NCIT_P108 "Colchicine-Site Binding Agent ABT-751" @default.
- NCIT_C2679 NCIT_P207 "C1134654" @default.
- NCIT_C2679 NCIT_P210 "141430-65-1" @default.
- NCIT_C2679 NCIT_P319 "WDT5V5OB9F" @default.
- NCIT_C2679 NCIT_P322 "CTRP" @default.
- NCIT_C2679 NCIT_P322 "FDA" @default.
- NCIT_C2679 NCIT_P322 "GDC" @default.
- NCIT_C2679 NCIT_P325 "A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called sulfonamides." @default.
- NCIT_C2679 NCIT_P329 "38646" @default.
- NCIT_C2679 NCIT_P330 "38646" @default.
- NCIT_C2679 NCIT_P366 "ABT-751" @default.
- NCIT_C2679 NCIT_P375 "Colchicine-Site Binding Agent ABT-751" @default.
- NCIT_C2679 NCIT_P399 "38646" @default.
- NCIT_C2679 NCIT_R124 NCIT_C17828 @default.
- NCIT_C2679 NCIT_R124 NCIT_C20480 @default.
- NCIT_C2679 NCIT_R124 NCIT_C40795 @default.
- NCIT_C2679 NCIT_R124 NCIT_C40798 @default.
- NCIT_C2679 normalizedInformationContent "100" @default.
- NCIT_C2679 referenceCount "1" @default.
- NCIT_C2679 hasExactSynonym "ABT-751" @default.
- NCIT_C2679 hasExactSynonym "Colchicine-Site Binding Agent ABT-751" @default.
- NCIT_C2679 hasExactSynonym "E 7010" @default.
- NCIT_C2679 hasExactSynonym "E-7010" @default.
- NCIT_C2679 hasExactSynonym "E7010" @default.
- NCIT_C2679 hasExactSynonym "N-[2-[(4-Hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide" @default.
- NCIT_C2679 inSubset NCIT_C116977 @default.
- NCIT_C2679 inSubset NCIT_C116978 @default.
- NCIT_C2679 inSubset NCIT_C128784 @default.
- NCIT_C2679 inSubset NCIT_C157711 @default.
- NCIT_C2679 inSubset NCIT_C157712 @default.
- NCIT_C2679 inSubset NCIT_C176424 @default.
- NCIT_C2679 inSubset NCIT_C177537 @default.
- NCIT_C2679 inSubset NCIT_C63923 @default.
- NCIT_C2679 type Class @default.
- NCIT_C2679 isDefinedBy ncit.owl @default.
- NCIT_C2679 label "Colchicine-Site Binding Agent ABT-751" @default.
- NCIT_C2679 subClassOf NCIT_C186664 @default.
- NCIT_C2679 subClassOf NCIT_C1908 @default.
- NCIT_C2679 subClassOf NCIT_C1909 @default.
- NCIT_C2679 subClassOf NCIT_C25974 @default.
- NCIT_C2679 subClassOf NCIT_C2679 @default.
- NCIT_C2679 subClassOf NCIT_C273 @default.
- NCIT_C2679 subClassOf NCIT_C274 @default.
- NCIT_C2679 subClassOf NCIT_C67421 @default.