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- NCIT_C2682 IAO_0000115 "A recombinant protein comprised of epitopes of the extracellular domains of human vascular endothelial growth factor receptors (VEGFR) fused to the constant region (Fc) of human IgG1 with potential antiangiogenic activity. Afilbercept, functioning as a soluble decoy receptor, binds to pro-angiogenic vascular endothelial growth factors (VEGFs), thereby preventing VEGFs from binding to their endogenous receptors. Disruption of the binding of VEGFs to their cellular receptors may result in the inhibition of tumor angiogenesis, metastasis, and ultimately tumor regression." @default.
- NCIT_C2682 NCIT_A32 NCIT_C1909 @default.
- NCIT_C2682 NCIT_A7 NCIT_C17293 @default.
- NCIT_C2682 NCIT_NHC0 "C2682" @default.
- NCIT_C2682 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C2682 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2682 NCIT_P107 "Ziv-Aflibercept" @default.
- NCIT_C2682 NCIT_P108 "Ziv-Aflibercept" @default.
- NCIT_C2682 NCIT_P175 "724770" @default.
- NCIT_C2682 NCIT_P207 "C1134659" @default.
- NCIT_C2682 NCIT_P210 "862111-32-8" @default.
- NCIT_C2682 NCIT_P319 "15C2VL427D" @default.
- NCIT_C2682 NCIT_P322 "CTRP" @default.
- NCIT_C2682 NCIT_P322 "FDA" @default.
- NCIT_C2682 NCIT_P322 "GDC" @default.
- NCIT_C2682 NCIT_P325 "A substance being studied in the treatment of several types of cancer. Vascular endothelial growth factor trap blocks the action of vascular endothelial growth factor (VEGF) and may prevent the growth of new blood vessels that tumors need to grow. It is a type of antiangiogenesis agent." @default.
- NCIT_C2682 NCIT_P329 "38652" @default.
- NCIT_C2682 NCIT_P330 "38652" @default.
- NCIT_C2682 NCIT_P366 "VEGF_Trap" @default.
- NCIT_C2682 NCIT_P375 "Ziv-Aflibercept" @default.
- NCIT_C2682 NCIT_P399 "38652" @default.
- NCIT_C2682 normalizedInformationContent "92.730304365937428" @default.
- NCIT_C2682 referenceCount "3" @default.
- NCIT_C2682 hasExactSynonym "AFLIBERCEPT" @default.
- NCIT_C2682 hasExactSynonym "AVE0005" @default.
- NCIT_C2682 hasExactSynonym "Aflibercept" @default.
- NCIT_C2682 hasExactSynonym "Eylea" @default.
- NCIT_C2682 hasExactSynonym "VEGF Trap R1R2" @default.
- NCIT_C2682 hasExactSynonym "VEGF Trap" @default.
- NCIT_C2682 hasExactSynonym "VEGF-Trap" @default.
- NCIT_C2682 hasExactSynonym "Vascular Endothelial Growth Factor Trap" @default.
- NCIT_C2682 hasExactSynonym "Zaltrap" @default.
- NCIT_C2682 hasExactSynonym "Ziv-Aflibercept" @default.
- NCIT_C2682 hasExactSynonym "aflibercept" @default.
- NCIT_C2682 hasExactSynonym "vascular endothelial growth factor trap" @default.
- NCIT_C2682 inSubset NCIT_C116977 @default.
- NCIT_C2682 inSubset NCIT_C116978 @default.
- NCIT_C2682 inSubset NCIT_C128784 @default.
- NCIT_C2682 inSubset NCIT_C157711 @default.
- NCIT_C2682 inSubset NCIT_C157712 @default.
- NCIT_C2682 inSubset NCIT_C176424 @default.
- NCIT_C2682 inSubset NCIT_C177537 @default.
- NCIT_C2682 inSubset NCIT_C63923 @default.
- NCIT_C2682 type Class @default.
- NCIT_C2682 isDefinedBy ncit.owl @default.
- NCIT_C2682 label "Ziv-Aflibercept" @default.
- NCIT_C2682 subClassOf NCIT_C163758 @default.
- NCIT_C2682 subClassOf NCIT_C1742 @default.
- NCIT_C2682 subClassOf NCIT_C1908 @default.
- NCIT_C2682 subClassOf NCIT_C1909 @default.
- NCIT_C2682 subClassOf NCIT_C1971 @default.
- NCIT_C2682 subClassOf NCIT_C198860 @default.
- NCIT_C2682 subClassOf NCIT_C2682 @default.
- NCIT_C2682 subClassOf NCIT_C274 @default.