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- NCIT_C2686 IAO_0000115 "A cancer vaccine adjuvant consisting of a recombinant fowlpox virus encoding human granulocyte-macrophage colony-stimulating factor (GM-CSF). GM-CSF binds to specific cell surface receptors on various immuno-hematopoietic cell types, enhancing their proliferation and differentiation and stimulating macrophage and dendritic cell functions in antigen presentation and antitumor cell-mediated immunity. Administration of recombinant fowlpox GM-CSF vaccine adjuvant may induce an immune response against tumor cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells." @default.
- NCIT_C2686 NCIT_A7 NCIT_C38991 @default.
- NCIT_C2686 NCIT_NHC0 "C2686" @default.
- NCIT_C2686 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2686 NCIT_P106 "Virus" @default.
- NCIT_C2686 NCIT_P107 "Recombinant Fowlpox GM-CSF Vaccine Adjuvant" @default.
- NCIT_C2686 NCIT_P108 "Recombinant Fowlpox GM-CSF Vaccine Adjuvant" @default.
- NCIT_C2686 NCIT_P175 "707299" @default.
- NCIT_C2686 NCIT_P207 "C1134686" @default.
- NCIT_C2686 NCIT_P322 "CTRP" @default.
- NCIT_C2686 NCIT_P329 "38680" @default.
- NCIT_C2686 NCIT_P330 "38680" @default.
- NCIT_C2686 NCIT_P366 "Fowlpox-Sargramostim" @default.
- NCIT_C2686 NCIT_P399 "38680" @default.
- NCIT_C2686 NCIT_R124 NCIT_C17710 @default.
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- NCIT_C2686 NCIT_R72 NCIT_C12508 @default.
- NCIT_C2686 NCIT_R72 NCIT_C12530 @default.
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- NCIT_C2686 NCIT_R72 NCIT_C12621 @default.
- NCIT_C2686 NCIT_R72 NCIT_C12657 @default.
- NCIT_C2686 NCIT_R72 NCIT_C21599 @default.
- NCIT_C2686 NCIT_R72 NCIT_C32725 @default.
- NCIT_C2686 normalizedInformationContent "90.826665450122817" @default.
- NCIT_C2686 referenceCount "4" @default.
- NCIT_C2686 hasExactSynonym "Fowlpox-Sargramostim" @default.
- NCIT_C2686 hasExactSynonym "Recombinant Fowlpox GM-CSF Vaccine Adjuvant" @default.
- NCIT_C2686 hasExactSynonym "rF-GM-CSF" @default.
- NCIT_C2686 hasExactSynonym "rF-Sargramostim" @default.
- NCIT_C2686 inSubset NCIT_C116977 @default.
- NCIT_C2686 inSubset NCIT_C116978 @default.
- NCIT_C2686 inSubset NCIT_C128784 @default.
- NCIT_C2686 inSubset NCIT_C176424 @default.
- NCIT_C2686 type Class @default.
- NCIT_C2686 isDefinedBy ncit.owl @default.
- NCIT_C2686 label "Recombinant Fowlpox GM-CSF Vaccine Adjuvant" @default.
- NCIT_C2686 subClassOf B2215ee3c09b1e3431876648e45588ff5 @default.
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- NCIT_C2686 subClassOf NCIT_C307 @default.
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- NCIT_C2686 subClassOf NCIT_C96404 @default.