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- NCIT_C2688 IAO_0000115 "A Cremophor EL-free, albumin-stabilized nanoparticle formulation of the natural taxane paclitaxel with antineoplastic activity. Paclitaxel binds to and stabilizes microtubules, preventing their depolymerization and so inhibiting cellular motility, mitosis, and replication. This formulation solubilizes paclitaxel without the use of the solvent Cremophor, thereby permitting the administration of larger doses of paclitaxel while avoiding the toxic effects associated with Cremophor." @default.
- NCIT_C2688 NCIT_A32 NCIT_C1909 @default.
- NCIT_C2688 NCIT_NHC0 "C2688" @default.
- NCIT_C2688 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2688 NCIT_P107 "Nab-paclitaxel" @default.
- NCIT_C2688 NCIT_P108 "Nab-paclitaxel" @default.
- NCIT_C2688 NCIT_P175 "736631" @default.
- NCIT_C2688 NCIT_P207 "C1134696" @default.
- NCIT_C2688 NCIT_P302 "Metastatic breast cancer" @default.
- NCIT_C2688 NCIT_P322 "CTRP" @default.
- NCIT_C2688 NCIT_P322 "GDC" @default.
- NCIT_C2688 NCIT_P325 "A drug used to treat breast cancer that has spread or that has come back within 6 months after chemotherapy. It is also being studied in the treatment of newly diagnosed breast cancer and other types of cancer. ABI-007 is a type of mitotic inhibitor." @default.
- NCIT_C2688 NCIT_P329 "38690" @default.
- NCIT_C2688 NCIT_P330 "38690" @default.
- NCIT_C2688 NCIT_P366 "ABI-007" @default.
- NCIT_C2688 NCIT_P375 "Nab-paclitaxel" @default.
- NCIT_C2688 NCIT_P399 "38690" @default.
- NCIT_C2688 NCIT_R124 NCIT_C17828 @default.
- NCIT_C2688 NCIT_R124 NCIT_C20480 @default.
- NCIT_C2688 NCIT_R124 NCIT_C40795 @default.
- NCIT_C2688 NCIT_R124 NCIT_C40798 @default.
- NCIT_C2688 normalizedInformationContent "84.132738204908478" @default.
- NCIT_C2688 referenceCount "11" @default.
- NCIT_C2688 hasExactSynonym "ABI 007" @default.
- NCIT_C2688 hasExactSynonym "ABI-007" @default.
- NCIT_C2688 hasExactSynonym "Abraxane" @default.
- NCIT_C2688 hasExactSynonym "Albumin-Stabilized Nanoparticle Paclitaxel" @default.
- NCIT_C2688 hasExactSynonym "Albumin-bound Paclitaxel" @default.
- NCIT_C2688 hasExactSynonym "Nab-paclitaxel" @default.
- NCIT_C2688 hasExactSynonym "Nanoparticle Albumin-bound Paclitaxel" @default.
- NCIT_C2688 hasExactSynonym "Nanoparticle Paclitaxel" @default.
- NCIT_C2688 hasExactSynonym "Paclitaxel Albumin" @default.
- NCIT_C2688 hasExactSynonym "Paclitaxel Nanoparticle Albumin-bound" @default.
- NCIT_C2688 hasExactSynonym "Paclitaxel Protein-Bound" @default.
- NCIT_C2688 hasExactSynonym "Protein-bound Paclitaxel" @default.
- NCIT_C2688 hasExactSynonym "nanoparticle paclitaxel" @default.
- NCIT_C2688 hasExactSynonym "paclitaxel albumin-stabilized nanoparticle formulation" @default.
- NCIT_C2688 hasExactSynonym "protein-bound paclitaxel" @default.
- NCIT_C2688 inSubset NCIT_C116977 @default.
- NCIT_C2688 inSubset NCIT_C116978 @default.
- NCIT_C2688 inSubset NCIT_C128784 @default.
- NCIT_C2688 inSubset NCIT_C157711 @default.
- NCIT_C2688 inSubset NCIT_C157712 @default.
- NCIT_C2688 inSubset NCIT_C176424 @default.
- NCIT_C2688 inSubset NCIT_C177537 @default.
- NCIT_C2688 type Class @default.
- NCIT_C2688 isDefinedBy ncit.owl @default.
- NCIT_C2688 label "Nab-paclitaxel" @default.
- NCIT_C2688 subClassOf NCIT_C186664 @default.
- NCIT_C2688 subClassOf NCIT_C1908 @default.
- NCIT_C2688 subClassOf NCIT_C1909 @default.
- NCIT_C2688 subClassOf NCIT_C25974 @default.
- NCIT_C2688 subClassOf NCIT_C2688 @default.
- NCIT_C2688 subClassOf NCIT_C273 @default.
- NCIT_C2688 subClassOf NCIT_C274 @default.
- NCIT_C2688 subClassOf NCIT_C61078 @default.
- NCIT_C2688 subClassOf NCIT_C67437 @default.