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- NCIT_C2700 IAO_0000115 "A partially purified preparation isolated from the thymus and containing several peptides. Human Thymosin-Fraction 5 (TF-5) possesses immunopotentiating properties and can correct many of the immunological deficiencies resulting from the lack of thymosin function in animal models and in humans. This agent enhances the spontaneous natural killer activity of normal human large granular lymphocytes; exhibits additive effects with recombinant IFN-alpha in enhancing natural killer activity in vitro and; enhances IL2 production, IL2 receptor expression, and IFN-gamma production in mitogen-stimulated large granular lymphocytes. TF-5 may also modulate the secretion of some hypothalamic peptides and pituitary hormones, including prolactin and growth hormone. (NCI04)" @default.
- NCIT_C2700 NCIT_NHC0 "C2700" @default.
- NCIT_C2700 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C2700 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2700 NCIT_P108 "Human Thymosin-Fraction 5" @default.
- NCIT_C2700 NCIT_P175 "350391" @default.
- NCIT_C2700 NCIT_P207 "C0076620" @default.
- NCIT_C2700 NCIT_P366 "Human_Thymosin-Fraction_5" @default.
- NCIT_C2700 normalizedInformationContent "100" @default.
- NCIT_C2700 referenceCount "1" @default.
- NCIT_C2700 hasExactSynonym "Human Thymosin-Fraction 5" @default.
- NCIT_C2700 hasExactSynonym "Thymosin Fraction 5" @default.
- NCIT_C2700 type Class @default.
- NCIT_C2700 isDefinedBy ncit.owl @default.
- NCIT_C2700 label "Human Thymosin-Fraction 5" @default.
- NCIT_C2700 subClassOf NCIT_C1908 @default.
- NCIT_C2700 subClassOf NCIT_C1909 @default.
- NCIT_C2700 subClassOf NCIT_C2700 @default.
- NCIT_C2700 subClassOf NCIT_C308 @default.