Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C2727> ?p ?o ?g. }
Showing items 1 to 38 of
38
with 100 items per page.
- NCIT_C2727 IAO_0000115 "A quinazolone compound with anti-tumor activity. PD-168393 is a cell-permeable, irreversible, and selective inhibitor of ligand-dependent epidermal growth factor (EGF) receptor (EGFR). This agent binds to the catalytic domain of EGFR with a 1:1 stoichiometry and inactivates the EGFR tyrosine kinase activity through alkylation of a cystine residue (Cys-773) within the ATP-binding pocket, thereby inhibiting proliferation of EGFR-expressing tumor cells." @default.
- NCIT_C2727 NCIT_A32 NCIT_C1909 @default.
- NCIT_C2727 NCIT_A7 NCIT_C17068 @default.
- NCIT_C2727 NCIT_NHC0 "C2727" @default.
- NCIT_C2727 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C2727 NCIT_P108 "EGFR Inhibitor PD-168393" @default.
- NCIT_C2727 NCIT_P207 "C1518781" @default.
- NCIT_C2727 NCIT_P210 "194423-15-9" @default.
- NCIT_C2727 NCIT_P319 "3R996Y9T0I" @default.
- NCIT_C2727 NCIT_P322 "FDA" @default.
- NCIT_C2727 NCIT_P322 "GDC" @default.
- NCIT_C2727 NCIT_P350 "C17H13BrN4O" @default.
- NCIT_C2727 NCIT_P366 "PD-168393" @default.
- NCIT_C2727 NCIT_P375 "EGFR Inhibitor PD-168393" @default.
- NCIT_C2727 normalizedInformationContent "100" @default.
- NCIT_C2727 referenceCount "1" @default.
- NCIT_C2727 hasExactSynonym "4-[(3-Bromophenyl)amino]-6-Acrylamidoquinazoline" @default.
- NCIT_C2727 hasExactSynonym "EGFR Inhibitor PD-168393" @default.
- NCIT_C2727 hasExactSynonym "PD 168 393" @default.
- NCIT_C2727 hasExactSynonym "PD-168393" @default.
- NCIT_C2727 inSubset NCIT_C128784 @default.
- NCIT_C2727 inSubset NCIT_C157711 @default.
- NCIT_C2727 inSubset NCIT_C157712 @default.
- NCIT_C2727 inSubset NCIT_C177537 @default.
- NCIT_C2727 inSubset NCIT_C63923 @default.
- NCIT_C2727 type Class @default.
- NCIT_C2727 isDefinedBy ncit.owl @default.
- NCIT_C2727 label "EGFR Inhibitor PD-168393" @default.
- NCIT_C2727 subClassOf NCIT_C1404 @default.
- NCIT_C2727 subClassOf NCIT_C163758 @default.
- NCIT_C2727 subClassOf NCIT_C163952 @default.
- NCIT_C2727 subClassOf NCIT_C1908 @default.
- NCIT_C2727 subClassOf NCIT_C1909 @default.
- NCIT_C2727 subClassOf NCIT_C1967 @default.
- NCIT_C2727 subClassOf NCIT_C2167 @default.
- NCIT_C2727 subClassOf NCIT_C2727 @default.
- NCIT_C2727 subClassOf NCIT_C274 @default.
- NCIT_C2727 subClassOf NCIT_C471 @default.