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- NCIT_C28557 IAO_0000115 "M Phase-Promoting Factor is a protein kinase complex that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2." @default.
- NCIT_C28557 NCIT_NHC0 "C28557" @default.
- NCIT_C28557 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C28557 NCIT_P106 "Enzyme" @default.
- NCIT_C28557 NCIT_P108 "M-Phase Promoting Factor" @default.
- NCIT_C28557 NCIT_P207 "C0079805" @default.
- NCIT_C28557 NCIT_P366 "M-Phase_Promoting_Factor" @default.
- NCIT_C28557 NCIT_P98 "M-phase promoting factor is a heterodimer of the serine/threonine protein kinase cyclin-dependent kinase 1 with cyclin b." @default.
- NCIT_C28557 NCIT_R45 NCIT_C14182 @default.
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- NCIT_C28557 NCIT_R45 NCIT_C25796 @default.
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- NCIT_C28557 NCIT_R53 NCIT_C28563 @default.
- NCIT_C28557 NCIT_R53 NCIT_C40800 @default.
- NCIT_C28557 normalizedInformationContent "89.350088392419622" @default.
- NCIT_C28557 referenceCount "5" @default.
- NCIT_C28557 hasExactSynonym "M Phase-Promoting Factor" @default.
- NCIT_C28557 hasExactSynonym "M-Phase Promoting Factor" @default.
- NCIT_C28557 hasExactSynonym "M-Phase-Promoting Factor" @default.
- NCIT_C28557 hasExactSynonym "MPF" @default.
- NCIT_C28557 hasExactSynonym "Maturation Promoting Factor" @default.
- NCIT_C28557 hasExactSynonym "Maturation-Promoting Factor" @default.
- NCIT_C28557 hasExactSynonym "Mitosis Promoting Factor" @default.
- NCIT_C28557 hasExactSynonym "Mitosis-Promoting Factor" @default.
- NCIT_C28557 type Class @default.
- NCIT_C28557 isDefinedBy ncit.owl @default.
- NCIT_C28557 label "M-Phase Promoting Factor" @default.
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- NCIT_C28557 subClassOf NCIT_C21176 @default.
- NCIT_C28557 subClassOf NCIT_C26548 @default.
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