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- NCIT_C28816 IAO_0000115 "The naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Alprostadil is a potent vasodilator agent that increases peripheral blood flow, inhibits platelet aggregation, and induces bronchodilation. Used in the treatment of erectile dysfunction, this agent produces corporal smooth muscle relaxation by binding to PGE receptors, resulting in the activation of adenylate cyclase and the subsequent accumulation of 3'5'-cAMP." @default.
- NCIT_C28816 NCIT_NHC0 "C28816" @default.
- NCIT_C28816 NCIT_P106 "Organic Chemical" @default.
- NCIT_C28816 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C28816 NCIT_P107 "Alprostadil" @default.
- NCIT_C28816 NCIT_P108 "Alprostadil" @default.
- NCIT_C28816 NCIT_P175 "165559" @default.
- NCIT_C28816 NCIT_P207 "C0002335" @default.
- NCIT_C28816 NCIT_P210 "745-65-3" @default.
- NCIT_C28816 NCIT_P302 "Erectile dysfunction; Patent ductus arteriosus" @default.
- NCIT_C28816 NCIT_P319 "F5TD010360" @default.
- NCIT_C28816 NCIT_P322 "CTRP" @default.
- NCIT_C28816 NCIT_P322 "FDA" @default.
- NCIT_C28816 NCIT_P325 "A drug that is used to treat impotence (inability to have an erection) and is being studied in the treatment of sexual problems in men who have had surgery for prostate cancer. It is a type of vasodilator." @default.
- NCIT_C28816 NCIT_P329 "360459" @default.
- NCIT_C28816 NCIT_P330 "360459" @default.
- NCIT_C28816 NCIT_P350 "C20H34O5" @default.
- NCIT_C28816 NCIT_P366 "Alprostadil" @default.
- NCIT_C28816 NCIT_P368 "CHEBI:15544" @default.
- NCIT_C28816 NCIT_P399 "360459" @default.
- NCIT_C28816 normalizedInformationContent "100" @default.
- NCIT_C28816 referenceCount "1" @default.
- NCIT_C28816 hasExactSynonym "(11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic Acid" @default.
- NCIT_C28816 hasExactSynonym "ALPROSTADIL" @default.
- NCIT_C28816 hasExactSynonym "Alprostadil" @default.
- NCIT_C28816 hasExactSynonym "Caverject" @default.
- NCIT_C28816 hasExactSynonym "MUSE" @default.
- NCIT_C28816 hasExactSynonym "Muse (intraurethral alprostadil suppository)" @default.
- NCIT_C28816 hasExactSynonym "PGE1" @default.
- NCIT_C28816 hasExactSynonym "Prostaglandin E1" @default.
- NCIT_C28816 hasExactSynonym "alprostadil" @default.
- NCIT_C28816 hasExactSynonym "prostaglandin E1" @default.
- NCIT_C28816 inSubset NCIT_C107631 @default.
- NCIT_C28816 inSubset NCIT_C116977 @default.
- NCIT_C28816 inSubset NCIT_C116978 @default.
- NCIT_C28816 inSubset NCIT_C176424 @default.
- NCIT_C28816 inSubset NCIT_C63923 @default.
- NCIT_C28816 type Class @default.
- NCIT_C28816 isDefinedBy ncit.owl @default.
- NCIT_C28816 label "Alprostadil" @default.
- NCIT_C28816 subClassOf NCIT_C157134 @default.
- NCIT_C28816 subClassOf NCIT_C1899 @default.
- NCIT_C28816 subClassOf NCIT_C1908 @default.
- NCIT_C28816 subClassOf NCIT_C1909 @default.
- NCIT_C28816 subClassOf NCIT_C28816 @default.
- NCIT_C28816 subClassOf NCIT_C463 @default.
- NCIT_C28816 subClassOf NCIT_C782 @default.
- NCIT_C28816 subClassOf NCIT_C78568 @default.