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- NCIT_C28825 IAO_0000115 "A synthetic quinazoline derivative, Anagrelide reduces platelet production through a decrease in megakaryocyte maturation. Anagrelide inhibits cyclic AMP phosphodiesterase, as well as ADP- and collagen-induced platelet aggregation. At therapeutic doses, it does not influence white cell counts or coagulation parameters. Anagrelide is used for treatment of essential thrombocythemia to reduce elevated platelet counts and the risk of thrombosis. (NCI04)" @default.
- NCIT_C28825 NCIT_A5 NCIT_C28826 @default.
- NCIT_C28825 NCIT_NHC0 "C28825" @default.
- NCIT_C28825 NCIT_P106 "Organic Chemical" @default.
- NCIT_C28825 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C28825 NCIT_P107 "Anagrelide" @default.
- NCIT_C28825 NCIT_P108 "Anagrelide" @default.
- NCIT_C28825 NCIT_P207 "C0051809" @default.
- NCIT_C28825 NCIT_P210 "68475-42-3" @default.
- NCIT_C28825 NCIT_P319 "K9X45X0051" @default.
- NCIT_C28825 NCIT_P322 "CTRP" @default.
- NCIT_C28825 NCIT_P322 "FDA" @default.
- NCIT_C28825 NCIT_P325 "A drug that is used to decrease the number of platelets in the blood in order to prevent blood clotting." @default.
- NCIT_C28825 NCIT_P350 "C10H7Cl2N3O" @default.
- NCIT_C28825 NCIT_P366 "Anagrelide" @default.
- NCIT_C28825 NCIT_P368 "CHEBI:142290" @default.
- NCIT_C28825 NCIT_P399 "810702" @default.
- NCIT_C28825 normalizedInformationContent "100" @default.
- NCIT_C28825 referenceCount "1" @default.
- NCIT_C28825 hasExactSynonym "ANAGRELIDE" @default.
- NCIT_C28825 hasExactSynonym "Anagrelide" @default.
- NCIT_C28825 hasExactSynonym "anagrelide" @default.
- NCIT_C28825 inSubset NCIT_C116977 @default.
- NCIT_C28825 inSubset NCIT_C116978 @default.
- NCIT_C28825 inSubset NCIT_C176424 @default.
- NCIT_C28825 inSubset NCIT_C63923 @default.
- NCIT_C28825 type Class @default.
- NCIT_C28825 isDefinedBy ncit.owl @default.
- NCIT_C28825 label "Anagrelide" @default.
- NCIT_C28825 subClassOf NCIT_C1327 @default.
- NCIT_C28825 subClassOf NCIT_C1908 @default.
- NCIT_C28825 subClassOf NCIT_C1909 @default.
- NCIT_C28825 subClassOf NCIT_C28825 @default.
- NCIT_C28825 subClassOf NCIT_C78275 @default.