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- NCIT_C28906 IAO_0000115 "A synthetic antihypertensive methoxyphenoxy- 2-propanol derivative with no intrinsic sympathomimetic activity, Carvedilol acts as a nonselective beta-adrenoceptor blocking agent (S(-) enantiomer) and as an alpha 1-adrenoceptor blocker (R(+) and S(-) enantiomers). Its acts more strongly on beta-receptors than on alpha 1-receptors, reduces peripheral vascular resistance by vasodilation, and prevents reflex tachycardia (beta-blockade) so that heart rate is either unchanged or decreased. Carvedilol also reduces renin release through beta-blockade. (NCI04)" @default.
- NCIT_C28906 NCIT_A5 NCIT_C65292 @default.
- NCIT_C28906 NCIT_NHC0 "C28906" @default.
- NCIT_C28906 NCIT_P106 "Organic Chemical" @default.
- NCIT_C28906 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C28906 NCIT_P107 "Carvedilol" @default.
- NCIT_C28906 NCIT_P108 "Carvedilol" @default.
- NCIT_C28906 NCIT_P207 "C0054836" @default.
- NCIT_C28906 NCIT_P210 "72956-09-3" @default.
- NCIT_C28906 NCIT_P319 "0K47UL67F2" @default.
- NCIT_C28906 NCIT_P322 "CTRP" @default.
- NCIT_C28906 NCIT_P322 "FDA" @default.
- NCIT_C28906 NCIT_P325 "A drug used to treat high blood pressure and certain heart problems. It is also being studied in the prevention and treatment of side effects caused by some anticancer drugs. Coreg blocks certain receptors on nerve cells and causes blood vessels to dilate (widen). It is a type of antihypertensive agent and a type of antianginal agent." @default.
- NCIT_C28906 NCIT_P329 "700417" @default.
- NCIT_C28906 NCIT_P330 "700417" @default.
- NCIT_C28906 NCIT_P350 "C24H26N2O4" @default.
- NCIT_C28906 NCIT_P366 "Carvedilol" @default.
- NCIT_C28906 NCIT_P368 "CHEBI:3441" @default.
- NCIT_C28906 NCIT_P399 "700417" @default.
- NCIT_C28906 NCIT_R122 NCIT_C16484 @default.
- NCIT_C28906 NCIT_R122 NCIT_C16486 @default.
- NCIT_C28906 NCIT_R122 NCIT_C16554 @default.
- NCIT_C28906 NCIT_R122 NCIT_C16865 @default.
- NCIT_C28906 NCIT_R122 NCIT_C16946 @default.
- NCIT_C28906 NCIT_R122 NCIT_C17021 @default.
- NCIT_C28906 NCIT_R122 NCIT_C17287 @default.
- NCIT_C28906 NCIT_R122 NCIT_C20027 @default.
- NCIT_C28906 NCIT_R122 NCIT_C26548 @default.
- NCIT_C28906 NCIT_R122 NCIT_C28459 @default.
- NCIT_C28906 normalizedInformationContent "100" @default.
- NCIT_C28906 referenceCount "1" @default.
- NCIT_C28906 hasExactSynonym "CARVEDILOL" @default.
- NCIT_C28906 hasExactSynonym "Carvedilol" @default.
- NCIT_C28906 hasExactSynonym "Coreg" @default.
- NCIT_C28906 inSubset NCIT_C116977 @default.
- NCIT_C28906 inSubset NCIT_C116978 @default.
- NCIT_C28906 inSubset NCIT_C176424 @default.
- NCIT_C28906 inSubset NCIT_C63923 @default.
- NCIT_C28906 type Class @default.
- NCIT_C28906 isDefinedBy ncit.owl @default.
- NCIT_C28906 label "Carvedilol" @default.
- NCIT_C28906 subClassOf B251ee82257388f482fe6d3078f7f17d9 @default.
- NCIT_C28906 subClassOf B5124d5871fc0fbb5fc8ee738a51810ba @default.
- NCIT_C28906 subClassOf NCIT_C1908 @default.
- NCIT_C28906 subClassOf NCIT_C1909 @default.
- NCIT_C28906 subClassOf NCIT_C28906 @default.
- NCIT_C28906 subClassOf NCIT_C29576 @default.
- NCIT_C28906 subClassOf NCIT_C29747 @default.
- NCIT_C28906 subClassOf NCIT_C72900 @default.
- NCIT_C28906 subClassOf NCIT_C78272 @default.