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- NCIT_C28913 IAO_0000115 "A beta-lactam antibiotic and first-generation cephalosporin with bactericidal activity. Cefazolin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis." @default.
- NCIT_C28913 NCIT_A5 NCIT_C47968 @default.
- NCIT_C28913 NCIT_NHC0 "C28913" @default.
- NCIT_C28913 NCIT_P106 "Antibiotic" @default.
- NCIT_C28913 NCIT_P106 "Organic Chemical" @default.
- NCIT_C28913 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C28913 NCIT_P107 "Cefazolin" @default.
- NCIT_C28913 NCIT_P108 "Cefazolin" @default.
- NCIT_C28913 NCIT_P207 "C0007546" @default.
- NCIT_C28913 NCIT_P210 "25953-19-9" @default.
- NCIT_C28913 NCIT_P319 "IHS69L0Y4T" @default.
- NCIT_C28913 NCIT_P322 "CTRP" @default.
- NCIT_C28913 NCIT_P322 "FDA" @default.
- NCIT_C28913 NCIT_P350 "C14H14N8O4S3" @default.
- NCIT_C28913 NCIT_P366 "Cefazolin" @default.
- NCIT_C28913 NCIT_P368 "CHEBI:474053" @default.
- NCIT_C28913 normalizedInformationContent "100" @default.
- NCIT_C28913 referenceCount "1" @default.
- NCIT_C28913 hasExactSynonym "(6R,7R)-3-(((5-Methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-7-(2-(1H-tetrazol-1-yl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid" @default.
- NCIT_C28913 hasExactSynonym "CEFAZOLIN" @default.
- NCIT_C28913 hasExactSynonym "Cefazolin" @default.
- NCIT_C28913 inSubset NCIT_C116977 @default.
- NCIT_C28913 inSubset NCIT_C116978 @default.
- NCIT_C28913 inSubset NCIT_C63923 @default.
- NCIT_C28913 type Class @default.
- NCIT_C28913 isDefinedBy ncit.owl @default.
- NCIT_C28913 label "Cefazolin" @default.
- NCIT_C28913 subClassOf NCIT_C1908 @default.
- NCIT_C28913 subClassOf NCIT_C1909 @default.
- NCIT_C28913 subClassOf NCIT_C254 @default.
- NCIT_C28913 subClassOf NCIT_C258 @default.
- NCIT_C28913 subClassOf NCIT_C260 @default.
- NCIT_C28913 subClassOf NCIT_C28913 @default.
- NCIT_C28913 subClassOf NCIT_C357 @default.