Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C28918> ?p ?o ?g. }
Showing items 1 to 27 of
27
with 100 items per page.
- NCIT_C28918 IAO_0000115 "A second generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefuroxime's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefuroxime inhibits bacterial septum and cell wall synthesis formation." @default.
- NCIT_C28918 NCIT_NHC0 "C28918" @default.
- NCIT_C28918 NCIT_P106 "Antibiotic" @default.
- NCIT_C28918 NCIT_P106 "Organic Chemical" @default.
- NCIT_C28918 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C28918 NCIT_P108 "Cefuroxime Axetil" @default.
- NCIT_C28918 NCIT_P207 "C0055015" @default.
- NCIT_C28918 NCIT_P210 "64544-07-6" @default.
- NCIT_C28918 NCIT_P319 "Z49QDT0J8Z" @default.
- NCIT_C28918 NCIT_P322 "FDA" @default.
- NCIT_C28918 NCIT_P350 "C20H22N4O10S" @default.
- NCIT_C28918 NCIT_P366 "Cefurexine_Axetil" @default.
- NCIT_C28918 normalizedInformationContent "100" @default.
- NCIT_C28918 referenceCount "1" @default.
- NCIT_C28918 hasExactSynonym "CEFUROXIME AXETIL" @default.
- NCIT_C28918 hasExactSynonym "Cefuroxime Axetil" @default.
- NCIT_C28918 inSubset NCIT_C63923 @default.
- NCIT_C28918 type Class @default.
- NCIT_C28918 isDefinedBy ncit.owl @default.
- NCIT_C28918 label "Cefuroxime Axetil" @default.
- NCIT_C28918 subClassOf NCIT_C1908 @default.
- NCIT_C28918 subClassOf NCIT_C1909 @default.
- NCIT_C28918 subClassOf NCIT_C254 @default.
- NCIT_C28918 subClassOf NCIT_C258 @default.
- NCIT_C28918 subClassOf NCIT_C260 @default.
- NCIT_C28918 subClassOf NCIT_C28918 @default.
- NCIT_C28918 subClassOf NCIT_C357 @default.