Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C28922> ?p ?o ?g. }
Showing items 1 to 26 of
26
with 100 items per page.
- NCIT_C28922 IAO_0000115 "A synthetic monohydrate of chloral with sedative, hypnotic, and anticonvulsive properties. Chloral hydrate is converted to the active compound trichloroethanol by hepatic alcohol dehydrogenase. The agent interacts with various neurotransmitter-operated ion channels, thereby enhancing gamma-aminobutyric acid (GABA)-A receptor mediated chloride currents and inhibiting amino acid receptor-activated ion currents. In addition, chloral hydrate enhances the agonistic effects of glycine receptors, inhibits AMPA-induced calcium influx in cortical neurons, and facilitates 5-HT 3 receptor-mediated currents in ganglionic neurons. Overall, this results in a depressive effect on the central nervous system." @default.
- NCIT_C28922 NCIT_NHC0 "C28922" @default.
- NCIT_C28922 NCIT_P106 "Organic Chemical" @default.
- NCIT_C28922 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C28922 NCIT_P108 "Chloral Hydrate" @default.
- NCIT_C28922 NCIT_P207 "C0008161" @default.
- NCIT_C28922 NCIT_P210 "302-17-0" @default.
- NCIT_C28922 NCIT_P319 "418M5916WG" @default.
- NCIT_C28922 NCIT_P322 "FDA" @default.
- NCIT_C28922 NCIT_P350 "C2H3Cl3O2" @default.
- NCIT_C28922 NCIT_P366 "Chloral_Hydrate" @default.
- NCIT_C28922 NCIT_P368 "CHEBI:28142" @default.
- NCIT_C28922 normalizedInformationContent "100" @default.
- NCIT_C28922 referenceCount "1" @default.
- NCIT_C28922 hasExactSynonym "CHLORAL HYDRATE" @default.
- NCIT_C28922 hasExactSynonym "Chloral Hydrate" @default.
- NCIT_C28922 inSubset NCIT_C63923 @default.
- NCIT_C28922 type Class @default.
- NCIT_C28922 isDefinedBy ncit.owl @default.
- NCIT_C28922 label "Chloral Hydrate" @default.
- NCIT_C28922 subClassOf NCIT_C1908 @default.
- NCIT_C28922 subClassOf NCIT_C1909 @default.
- NCIT_C28922 subClassOf NCIT_C2199 @default.
- NCIT_C28922 subClassOf NCIT_C241 @default.
- NCIT_C28922 subClassOf NCIT_C28922 @default.
- NCIT_C28922 subClassOf NCIT_C78272 @default.