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- NCIT_C28934 IAO_0000115 "The propionate salt form of clobetasol, a topical synthetic corticosteroid with anti-inflammatory, anti-pruritic, and vasoconstrictive properties. Clobetasol propionate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. This results in synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators. Specifically, clobetasol propionate appears to induce phospholipase A2 inhibitory proteins, thereby controlling the release of the inflammatory precursor arachidonic acid from membrane phospholipids by phospholipase A2." @default.
- NCIT_C28934 NCIT_A7 NCIT_C17071 @default.
- NCIT_C28934 NCIT_NHC0 "C28934" @default.
- NCIT_C28934 NCIT_P106 "Organic Chemical" @default.
- NCIT_C28934 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C28934 NCIT_P107 "Clobetasol Propionate" @default.
- NCIT_C28934 NCIT_P108 "Clobetasol Propionate" @default.
- NCIT_C28934 NCIT_P207 "C0055895" @default.
- NCIT_C28934 NCIT_P210 "25122-46-7" @default.
- NCIT_C28934 NCIT_P302 "Psoriasis, Eczema" @default.
- NCIT_C28934 NCIT_P319 "779619577M" @default.
- NCIT_C28934 NCIT_P322 "CTRP" @default.
- NCIT_C28934 NCIT_P322 "FDA" @default.
- NCIT_C28934 NCIT_P329 "547027" @default.
- NCIT_C28934 NCIT_P330 "547027" @default.
- NCIT_C28934 NCIT_P350 "C25H32ClFO5" @default.
- NCIT_C28934 NCIT_P366 "Clobetasol_Propionate" @default.
- NCIT_C28934 NCIT_P368 "CHEBI:31414" @default.
- NCIT_C28934 NCIT_P399 "547027" @default.
- NCIT_C28934 NCIT_R122 NCIT_C16484 @default.
- NCIT_C28934 NCIT_R122 NCIT_C16486 @default.
- NCIT_C28934 NCIT_R122 NCIT_C16554 @default.
- NCIT_C28934 NCIT_R122 NCIT_C16865 @default.
- NCIT_C28934 NCIT_R122 NCIT_C16946 @default.
- NCIT_C28934 NCIT_R122 NCIT_C17021 @default.
- NCIT_C28934 NCIT_R122 NCIT_C17573 @default.
- NCIT_C28934 NCIT_R122 NCIT_C20027 @default.
- NCIT_C28934 NCIT_R122 NCIT_C26548 @default.
- NCIT_C28934 NCIT_R122 NCIT_C28459 @default.
- NCIT_C28934 normalizedInformationContent "100" @default.
- NCIT_C28934 referenceCount "1" @default.
- NCIT_C28934 hasExactSynonym "CLOBETASOL PROPIONATE" @default.
- NCIT_C28934 hasExactSynonym "Clobetasol Propionate" @default.
- NCIT_C28934 hasExactSynonym "Olux-E" @default.
- NCIT_C28934 inSubset NCIT_C116977 @default.
- NCIT_C28934 inSubset NCIT_C116978 @default.
- NCIT_C28934 inSubset NCIT_C176424 @default.
- NCIT_C28934 inSubset NCIT_C63923 @default.
- NCIT_C28934 type Class @default.
- NCIT_C28934 isDefinedBy ncit.owl @default.
- NCIT_C28934 label "Clobetasol Propionate" @default.
- NCIT_C28934 subClassOf NCIT_C147908 @default.
- NCIT_C28934 subClassOf NCIT_C1636 @default.
- NCIT_C28934 subClassOf NCIT_C1908 @default.
- NCIT_C28934 subClassOf NCIT_C1909 @default.
- NCIT_C28934 subClassOf NCIT_C211 @default.
- NCIT_C28934 subClassOf NCIT_C2364 @default.
- NCIT_C28934 subClassOf NCIT_C28934 @default.
- NCIT_C28934 subClassOf NCIT_C308 @default.
- NCIT_C28934 subClassOf NCIT_C521 @default.
- NCIT_C28934 subClassOf NCIT_C548 @default.
- NCIT_C28934 subClassOf NCIT_C574 @default.