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- NCIT_C28989 IAO_0000115 "A topical retinoid-like compound, chemically similar to vitamin A. Although the exact mechanism of action is unknown, adapalene binds to specific retinoic acid receptors in the nucleus, leading to specific gene expression. This agent stimulates skin growth through modulation of cellular differentiation, inflammatory processes and keratinization of follicular epithelial cells. Adapalene may increase dermal sensitivity to ultraviolet radiation. (NCI04)" @default.
- NCIT_C28989 NCIT_NHC0 "C28989" @default.
- NCIT_C28989 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C28989 NCIT_P108 "Adapalene" @default.
- NCIT_C28989 NCIT_P207 "C0165631" @default.
- NCIT_C28989 NCIT_P210 "106685-40-9" @default.
- NCIT_C28989 NCIT_P302 "Topical treatment of acne vulgaris" @default.
- NCIT_C28989 NCIT_P319 "1L4806J2QF" @default.
- NCIT_C28989 NCIT_P322 "FDA" @default.
- NCIT_C28989 NCIT_P350 "C28H28O3" @default.
- NCIT_C28989 NCIT_P366 "Adapalene" @default.
- NCIT_C28989 NCIT_P368 "CHEBI:31174" @default.
- NCIT_C28989 NCIT_P399 "805120" @default.
- NCIT_C28989 normalizedInformationContent "100" @default.
- NCIT_C28989 referenceCount "1" @default.
- NCIT_C28989 hasExactSynonym "6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid" @default.
- NCIT_C28989 hasExactSynonym "6-(4-Methoxy-3-tricyclo(3.3.1.13,7)dec-1-ylphenyl)-2-naphthalenecarboxylic Acid" @default.
- NCIT_C28989 hasExactSynonym "ADAPALENE" @default.
- NCIT_C28989 hasExactSynonym "Adapalene" @default.
- NCIT_C28989 hasExactSynonym "CD271" @default.
- NCIT_C28989 hasExactSynonym "Differin" @default.
- NCIT_C28989 inSubset NCIT_C176424 @default.
- NCIT_C28989 inSubset NCIT_C63923 @default.
- NCIT_C28989 type Class @default.
- NCIT_C28989 isDefinedBy ncit.owl @default.
- NCIT_C28989 label "Adapalene" @default.
- NCIT_C28989 subClassOf NCIT_C129820 @default.
- NCIT_C28989 subClassOf NCIT_C163758 @default.
- NCIT_C28989 subClassOf NCIT_C1908 @default.
- NCIT_C28989 subClassOf NCIT_C1909 @default.
- NCIT_C28989 subClassOf NCIT_C1934 @default.
- NCIT_C28989 subClassOf NCIT_C2122 @default.
- NCIT_C28989 subClassOf NCIT_C274 @default.
- NCIT_C28989 subClassOf NCIT_C28989 @default.
- NCIT_C28989 subClassOf NCIT_C308 @default.
- NCIT_C28989 subClassOf NCIT_C804 @default.