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- NCIT_C29015 IAO_0000115 "An unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body." @default.
- NCIT_C29015 NCIT_A5 NCIT_C66875 @default.
- NCIT_C29015 NCIT_NHC0 "C29015" @default.
- NCIT_C29015 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29015 NCIT_P108 "Dyclonine" @default.
- NCIT_C29015 NCIT_P207 "C0058831" @default.
- NCIT_C29015 NCIT_P210 "586-60-7" @default.
- NCIT_C29015 NCIT_P319 "078A24Q30O" @default.
- NCIT_C29015 NCIT_P322 "FDA" @default.
- NCIT_C29015 NCIT_P350 "C18H27NO2" @default.
- NCIT_C29015 NCIT_P366 "Dyclonine" @default.
- NCIT_C29015 NCIT_P368 "CHEBI:4724" @default.
- NCIT_C29015 normalizedInformationContent "100" @default.
- NCIT_C29015 referenceCount "1" @default.
- NCIT_C29015 hasExactSynonym "1-Propanone,1-(4-butoxyphenyl)-3-(1-piperidinyl)-" @default.
- NCIT_C29015 hasExactSynonym "DYCLONINE" @default.
- NCIT_C29015 hasExactSynonym "Dyclonine" @default.
- NCIT_C29015 inSubset NCIT_C63923 @default.
- NCIT_C29015 type Class @default.
- NCIT_C29015 isDefinedBy ncit.owl @default.
- NCIT_C29015 label "Dyclonine" @default.
- NCIT_C29015 subClassOf NCIT_C1908 @default.
- NCIT_C29015 subClassOf NCIT_C1909 @default.
- NCIT_C29015 subClassOf NCIT_C245 @default.
- NCIT_C29015 subClassOf NCIT_C29015 @default.
- NCIT_C29015 subClassOf NCIT_C78272 @default.