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- NCIT_C29027 IAO_0000115 "A synthetic non-nucleoside reverse transcriptase (RT) inhibitor with antiviral activity. Efavirenz binds directly to the human immunodeficiency virus type 1 (HIV-1) RT, an RNA-dependent DNA polymerase, blocking its function in viral DNA replication. In combination with other antiretroviral drugs, this agent has been shown to significantly reduce HIV viral load, retarding or preventing damage to the immune system and reducing the risk of developing AIDS. Efavirenz induces activity of the cytochrome P450 system, accelerating its own metabolism." @default.
- NCIT_C29027 NCIT_NHC0 "C29027" @default.
- NCIT_C29027 NCIT_P106 "Organic Chemical" @default.
- NCIT_C29027 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29027 NCIT_P107 "Efavirenz" @default.
- NCIT_C29027 NCIT_P108 "Efavirenz" @default.
- NCIT_C29027 NCIT_P207 "C0674428" @default.
- NCIT_C29027 NCIT_P210 "154598-52-4" @default.
- NCIT_C29027 NCIT_P319 "JE6H2O27P8" @default.
- NCIT_C29027 NCIT_P322 "CTRP" @default.
- NCIT_C29027 NCIT_P322 "FDA" @default.
- NCIT_C29027 NCIT_P325 "A drug used with other drugs to treat infection with the human immunodeficiency virus (HIV). It blocks HIV from making copies of itself. It is a type of non-nucleoside reverse transcriptase inhibitor and a type of antiviral agent." @default.
- NCIT_C29027 NCIT_P329 "540650" @default.
- NCIT_C29027 NCIT_P330 "540650" @default.
- NCIT_C29027 NCIT_P350 "C14H9ClF3NO2" @default.
- NCIT_C29027 NCIT_P366 "Efavirenz" @default.
- NCIT_C29027 NCIT_P368 "CHEBI:119486" @default.
- NCIT_C29027 NCIT_P399 "540650" @default.
- NCIT_C29027 NCIT_R122 NCIT_C16484 @default.
- NCIT_C29027 NCIT_R122 NCIT_C16486 @default.
- NCIT_C29027 NCIT_R122 NCIT_C16554 @default.
- NCIT_C29027 NCIT_R122 NCIT_C16865 @default.
- NCIT_C29027 NCIT_R122 NCIT_C16946 @default.
- NCIT_C29027 NCIT_R122 NCIT_C17021 @default.
- NCIT_C29027 NCIT_R122 NCIT_C20027 @default.
- NCIT_C29027 NCIT_R122 NCIT_C26548 @default.
- NCIT_C29027 NCIT_R122 NCIT_C28459 @default.
- NCIT_C29027 NCIT_R122 NCIT_C40050 @default.
- NCIT_C29027 normalizedInformationContent "100" @default.
- NCIT_C29027 referenceCount "1" @default.
- NCIT_C29027 hasExactSynonym "DMP-266" @default.
- NCIT_C29027 hasExactSynonym "EFAVIRENZ" @default.
- NCIT_C29027 hasExactSynonym "Efavirenz" @default.
- NCIT_C29027 hasExactSynonym "L743726" @default.
- NCIT_C29027 hasExactSynonym "MK-0831" @default.
- NCIT_C29027 hasExactSynonym "Sustiva" @default.
- NCIT_C29027 hasExactSynonym "efavirenz" @default.
- NCIT_C29027 inSubset NCIT_C116977 @default.
- NCIT_C29027 inSubset NCIT_C116978 @default.
- NCIT_C29027 inSubset NCIT_C176424 @default.
- NCIT_C29027 inSubset NCIT_C63923 @default.
- NCIT_C29027 type Class @default.
- NCIT_C29027 isDefinedBy ncit.owl @default.
- NCIT_C29027 label "Efavirenz" @default.
- NCIT_C29027 subClassOf Baad8eb89b5f3a00899f0af9b2f51626d @default.
- NCIT_C29027 subClassOf Bad0f469a526574079e0d6ec24d66d381 @default.
- NCIT_C29027 subClassOf NCIT_C1589 @default.
- NCIT_C29027 subClassOf NCIT_C1908 @default.
- NCIT_C29027 subClassOf NCIT_C1909 @default.
- NCIT_C29027 subClassOf NCIT_C254 @default.
- NCIT_C29027 subClassOf NCIT_C281 @default.
- NCIT_C29027 subClassOf NCIT_C29027 @default.
- NCIT_C29027 subClassOf NCIT_C471 @default.
- NCIT_C29027 subClassOf NCIT_C97453 @default.