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- NCIT_C29083 IAO_0000115 "A combination preparation containing guaifenesin and the opioid agonist dextrometorphan with expectorant and antitussive activities, respectively. Guaifenesin works by drawing water into respiratory tracts, by which reducing adhesiveness and surface tension of mucus as well as increasing hydration of mucus, thereby reducing the viscosity of mucus and making cough more productive. Dextrometorphan, a synthetic, methylated dextrorotary analogue of levorphanol, exhibits antitussive activity by activating opioid receptors in the cough center in the central nervous system, thereby raising the threshold for coughing." @default.
- NCIT_C29083 NCIT_NHC0 "C29083" @default.
- NCIT_C29083 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29083 NCIT_P108 "Guaifenesin-DM" @default.
- NCIT_C29083 NCIT_P207 "C0717689" @default.
- NCIT_C29083 NCIT_P366 "Guaifenisin-DM" @default.
- NCIT_C29083 normalizedInformationContent "100" @default.
- NCIT_C29083 referenceCount "1" @default.
- NCIT_C29083 hasExactSynonym "Guaifenesin-DM" @default.
- NCIT_C29083 hasExactSynonym "Guaifenesin-Dextromethorphan" @default.
- NCIT_C29083 hasExactSynonym "Robitussin DM" @default.
- NCIT_C29083 type Class @default.
- NCIT_C29083 isDefinedBy ncit.owl @default.
- NCIT_C29083 label "Guaifenesin-DM" @default.
- NCIT_C29083 subClassOf NCIT_C1908 @default.
- NCIT_C29083 subClassOf NCIT_C1909 @default.
- NCIT_C29083 subClassOf NCIT_C29083 @default.
- NCIT_C29083 subClassOf NCIT_C29629 @default.
- NCIT_C29083 subClassOf NCIT_C29630 @default.