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- NCIT_C29130 IAO_0000115 "A nonpeptide angiotensin II antagonist with antihypertensive activity. Irbesartan selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor. Angiotensin II stimulates aldosterone synthesis and secretion by adrenal cortex, which decreases the excretion of sodium and increases the excretion of potassium. Angiotensin II also acts as a vasoconstrictor in vascular smooth muscle. (NCI05)" @default.
- NCIT_C29130 NCIT_NHC0 "C29130" @default.
- NCIT_C29130 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29130 NCIT_P108 "Irbesartan" @default.
- NCIT_C29130 NCIT_P207 "C0595301" @default.
- NCIT_C29130 NCIT_P210 "138402-11-6" @default.
- NCIT_C29130 NCIT_P319 "J0E2756Z7N" @default.
- NCIT_C29130 NCIT_P322 "FDA" @default.
- NCIT_C29130 NCIT_P350 "C25H28N6O" @default.
- NCIT_C29130 NCIT_P366 "Irbesartan" @default.
- NCIT_C29130 NCIT_P368 "CHEBI:5959" @default.
- NCIT_C29130 NCIT_R122 NCIT_C16484 @default.
- NCIT_C29130 NCIT_R122 NCIT_C16486 @default.
- NCIT_C29130 NCIT_R122 NCIT_C16554 @default.
- NCIT_C29130 NCIT_R122 NCIT_C16865 @default.
- NCIT_C29130 NCIT_R122 NCIT_C16946 @default.
- NCIT_C29130 NCIT_R122 NCIT_C17021 @default.
- NCIT_C29130 NCIT_R122 NCIT_C20027 @default.
- NCIT_C29130 NCIT_R122 NCIT_C26548 @default.
- NCIT_C29130 NCIT_R122 NCIT_C28459 @default.
- NCIT_C29130 NCIT_R122 NCIT_C28750 @default.
- NCIT_C29130 normalizedInformationContent "100" @default.
- NCIT_C29130 referenceCount "1" @default.
- NCIT_C29130 hasExactSynonym "Avapro" @default.
- NCIT_C29130 hasExactSynonym "IRBESARTAN" @default.
- NCIT_C29130 hasExactSynonym "Irbesartan" @default.
- NCIT_C29130 inSubset NCIT_C173381 @default.
- NCIT_C29130 inSubset NCIT_C173383 @default.
- NCIT_C29130 inSubset NCIT_C63923 @default.
- NCIT_C29130 type Class @default.
- NCIT_C29130 isDefinedBy ncit.owl @default.
- NCIT_C29130 label "Irbesartan" @default.
- NCIT_C29130 subClassOf B7693f9da0cc78f3a1b303455fb19ef5e @default.
- NCIT_C29130 subClassOf Be43eb4c4c1d405f7da06c89a67a89551 @default.
- NCIT_C29130 subClassOf NCIT_C1908 @default.
- NCIT_C29130 subClassOf NCIT_C1909 @default.
- NCIT_C29130 subClassOf NCIT_C270 @default.
- NCIT_C29130 subClassOf NCIT_C29130 @default.
- NCIT_C29130 subClassOf NCIT_C66930 @default.
- NCIT_C29130 subClassOf NCIT_C78274 @default.