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- NCIT_C29159 IAO_0000115 "An orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Lisinopril, a synthetic peptide derivative, specifically and competitively inhibits ACE, which results in a decrease in the production of the potent vasoconstrictor angiotensin II and, so, diminished vasopressor activity. In addition, angiotensin II-stimulated aldosterone secretion by the adrenal cortex is decreased which results in a decrease in sodium and water retention and an increase in serum potassium." @default.
- NCIT_C29159 NCIT_A7 NCIT_C91297 @default.
- NCIT_C29159 NCIT_NHC0 "C29159" @default.
- NCIT_C29159 NCIT_P106 "Organic Chemical" @default.
- NCIT_C29159 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29159 NCIT_P107 "Lisinopril" @default.
- NCIT_C29159 NCIT_P108 "Lisinopril" @default.
- NCIT_C29159 NCIT_P207 "C0065374" @default.
- NCIT_C29159 NCIT_P210 "83915-83-7" @default.
- NCIT_C29159 NCIT_P319 "E7199S1YWR" @default.
- NCIT_C29159 NCIT_P322 "CTRP" @default.
- NCIT_C29159 NCIT_P322 "FDA" @default.
- NCIT_C29159 NCIT_P325 "A drug used to treat high blood pressure and certain heart conditions. It is also being studied in the prevention and treatment of side effects caused by some anticancer drugs. It blocks certain enzymes that cause blood vessels to constrict (narrow). It is a type of angiotensin-converting enzyme (ACE) inhibitor." @default.
- NCIT_C29159 NCIT_P329 "658710" @default.
- NCIT_C29159 NCIT_P330 "658710" @default.
- NCIT_C29159 NCIT_P350 "C21H31N3O5.2H2O" @default.
- NCIT_C29159 NCIT_P366 "Lisinopril" @default.
- NCIT_C29159 NCIT_P368 "CHEBI:6503" @default.
- NCIT_C29159 NCIT_P399 "658710" @default.
- NCIT_C29159 normalizedInformationContent "100" @default.
- NCIT_C29159 referenceCount "1" @default.
- NCIT_C29159 hasExactSynonym "LISINOPRIL" @default.
- NCIT_C29159 hasExactSynonym "Lisinopril" @default.
- NCIT_C29159 hasExactSynonym "N2-[(1S)-1-Carboxy-3-phenylpropyl]-L-lysyl-L-proline, Dihydrate" @default.
- NCIT_C29159 hasExactSynonym "Prinivil" @default.
- NCIT_C29159 hasExactSynonym "Zestril" @default.
- NCIT_C29159 hasExactSynonym "lisinopril" @default.
- NCIT_C29159 inSubset NCIT_C116977 @default.
- NCIT_C29159 inSubset NCIT_C116978 @default.
- NCIT_C29159 inSubset NCIT_C176424 @default.
- NCIT_C29159 inSubset NCIT_C63923 @default.
- NCIT_C29159 type Class @default.
- NCIT_C29159 isDefinedBy ncit.owl @default.
- NCIT_C29159 label "Lisinopril" @default.
- NCIT_C29159 subClassOf NCIT_C1908 @default.
- NCIT_C29159 subClassOf NCIT_C1909 @default.
- NCIT_C29159 subClassOf NCIT_C247 @default.
- NCIT_C29159 subClassOf NCIT_C270 @default.
- NCIT_C29159 subClassOf NCIT_C29159 @default.
- NCIT_C29159 subClassOf NCIT_C471 @default.
- NCIT_C29159 subClassOf NCIT_C78274 @default.
- NCIT_C29159 subClassOf NCIT_C783 @default.