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- NCIT_C29165 IAO_0000115 "The potassium salt of losartan, a non-peptide angiotensin II receptor antagonist with antihypertensive activity. Losartan selectively and competitively binds to the angiotensin II receptor (type AT1) and blocks the binding of angiotensin II to the receptor, thus promoting vasodilatation and counteracting the effects of aldosterone. Converted from angiotensin I by angiotensin-converting enzyme (ACE), angiotensin II stimulates the adrenal cortex to synthesize and secrete aldosterone, decreasing sodium excretion and increasing potassium excretion, and acts as a vasoconstrictor in vascular smooth muscle." @default.
- NCIT_C29165 NCIT_A6 NCIT_C66869 @default.
- NCIT_C29165 NCIT_A7 NCIT_C179874 @default.
- NCIT_C29165 NCIT_NHC0 "C29165" @default.
- NCIT_C29165 NCIT_P106 "Organic Chemical" @default.
- NCIT_C29165 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29165 NCIT_P107 "Losartan Potassium" @default.
- NCIT_C29165 NCIT_P108 "Losartan Potassium" @default.
- NCIT_C29165 NCIT_P207 "C0700492" @default.
- NCIT_C29165 NCIT_P210 "124750-99-8" @default.
- NCIT_C29165 NCIT_P319 "3ST302B24A" @default.
- NCIT_C29165 NCIT_P322 "CTRP" @default.
- NCIT_C29165 NCIT_P322 "FDA" @default.
- NCIT_C29165 NCIT_P325 "A drug used to treat high blood pressure. Cozaar blocks the action of chemicals that make blood vessels constrict (get narrower). It is a type of angiotensin II receptor antagonist." @default.
- NCIT_C29165 NCIT_P329 "640981" @default.
- NCIT_C29165 NCIT_P330 "640981" @default.
- NCIT_C29165 NCIT_P350 "C22H22ClN6O.K" @default.
- NCIT_C29165 NCIT_P366 "Losartan_Potassium" @default.
- NCIT_C29165 NCIT_P399 "640981" @default.
- NCIT_C29165 normalizedInformationContent "100" @default.
- NCIT_C29165 referenceCount "1" @default.
- NCIT_C29165 hasExactSynonym "2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol, Monopotassium Salt" @default.
- NCIT_C29165 hasExactSynonym "Cozaar" @default.
- NCIT_C29165 hasExactSynonym "LOSARTAN POTASSIUM" @default.
- NCIT_C29165 hasExactSynonym "Losartan Potassium" @default.
- NCIT_C29165 hasExactSynonym "losartan potassium" @default.
- NCIT_C29165 hasExactSynonym "losartan" @default.
- NCIT_C29165 inSubset NCIT_C116977 @default.
- NCIT_C29165 inSubset NCIT_C116978 @default.
- NCIT_C29165 inSubset NCIT_C173381 @default.
- NCIT_C29165 inSubset NCIT_C173383 @default.
- NCIT_C29165 inSubset NCIT_C176424 @default.
- NCIT_C29165 inSubset NCIT_C63923 @default.
- NCIT_C29165 type Class @default.
- NCIT_C29165 isDefinedBy ncit.owl @default.
- NCIT_C29165 label "Losartan Potassium" @default.
- NCIT_C29165 subClassOf NCIT_C1908 @default.
- NCIT_C29165 subClassOf NCIT_C1909 @default.
- NCIT_C29165 subClassOf NCIT_C270 @default.
- NCIT_C29165 subClassOf NCIT_C29165 @default.
- NCIT_C29165 subClassOf NCIT_C66930 @default.
- NCIT_C29165 subClassOf NCIT_C78274 @default.