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- NCIT_C29245 IAO_0000115 "The hydrochloride salt form of meclizine, a synthetic piperazine with anti-emetic, sedative and histamine H1 antagonistic properties. Meclizine hydrochloride blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial and gastrointestinal smooth muscles, including vasodilation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscles. Meclizine hydrochloride may exert its antiemetic effects by its anticholinergic actions or due to a direct effect on the medullary chemoreceptive trigger zone." @default.
- NCIT_C29245 NCIT_A6 NCIT_C61610 @default.
- NCIT_C29245 NCIT_NHC0 "C29245" @default.
- NCIT_C29245 NCIT_P106 "Organic Chemical" @default.
- NCIT_C29245 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29245 NCIT_P108 "Meclizine Hydrochloride" @default.
- NCIT_C29245 NCIT_P175 "169189" @default.
- NCIT_C29245 NCIT_P207 "C0282227" @default.
- NCIT_C29245 NCIT_P210 "31884-77-2" @default.
- NCIT_C29245 NCIT_P319 "HDP7W44CIO" @default.
- NCIT_C29245 NCIT_P322 "FDA" @default.
- NCIT_C29245 NCIT_P329 "793974" @default.
- NCIT_C29245 NCIT_P330 "793974" @default.
- NCIT_C29245 NCIT_P350 "C25H27ClN2.2HCl.H2O" @default.
- NCIT_C29245 NCIT_P366 "Meclizine_Hydrochloride" @default.
- NCIT_C29245 NCIT_P399 "793974" @default.
- NCIT_C29245 normalizedInformationContent "100" @default.
- NCIT_C29245 referenceCount "1" @default.
- NCIT_C29245 hasExactSynonym "1-[(4-Chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine Dihydrochloride Monohydrate" @default.
- NCIT_C29245 hasExactSynonym "Antivert" @default.
- NCIT_C29245 hasExactSynonym "Bonine" @default.
- NCIT_C29245 hasExactSynonym "MECLIZINE HYDROCHLORIDE" @default.
- NCIT_C29245 hasExactSynonym "Meclizine Dihydrochloride Monohydrate" @default.
- NCIT_C29245 hasExactSynonym "Meclizine HCl" @default.
- NCIT_C29245 hasExactSynonym "Meclizine Hydrochloride" @default.
- NCIT_C29245 inSubset NCIT_C176424 @default.
- NCIT_C29245 inSubset NCIT_C63923 @default.
- NCIT_C29245 type Class @default.
- NCIT_C29245 isDefinedBy ncit.owl @default.
- NCIT_C29245 label "Meclizine Hydrochloride" @default.
- NCIT_C29245 subClassOf NCIT_C1908 @default.
- NCIT_C29245 subClassOf NCIT_C1909 @default.
- NCIT_C29245 subClassOf NCIT_C267 @default.
- NCIT_C29245 subClassOf NCIT_C29245 @default.
- NCIT_C29245 subClassOf NCIT_C29578 @default.
- NCIT_C29245 subClassOf NCIT_C308 @default.
- NCIT_C29245 subClassOf NCIT_C78272 @default.