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- NCIT_C29265 IAO_0000115 "A synthetic tetracyclic derivative of the piperazino-azepines with antidepressant activity. Although its mechanism of action is unknown, mirtazapine enhances central adrenergic and serotonergic transmission, possibly by acting as an antagonist at central presynaptic alpha 2 adrenergic inhibitory autoreceptors and heteroreceptors. This agent is a potent antagonist of 5-hydroxytryptamine type 2 (5-HT2), 5-HT3, and histamine 1 (H1) receptors, and a moderate antagonist of peripheral alpha 1 adrenergic and muscarinic receptors." @default.
- NCIT_C29265 NCIT_NHC0 "C29265" @default.
- NCIT_C29265 NCIT_P106 "Organic Chemical" @default.
- NCIT_C29265 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29265 NCIT_P107 "Mirtazapine" @default.
- NCIT_C29265 NCIT_P108 "Mirtazapine" @default.
- NCIT_C29265 NCIT_P207 "C0049506" @default.
- NCIT_C29265 NCIT_P210 "61337-67-5" @default.
- NCIT_C29265 NCIT_P210 "85650-52-8" @default.
- NCIT_C29265 NCIT_P319 "A051Q2099Q" @default.
- NCIT_C29265 NCIT_P322 "CTRP" @default.
- NCIT_C29265 NCIT_P322 "FDA" @default.
- NCIT_C29265 NCIT_P325 "A drug used to treat depression. It belongs to the family of drugs called antidepressant agents." @default.
- NCIT_C29265 NCIT_P329 "559298" @default.
- NCIT_C29265 NCIT_P330 "559298" @default.
- NCIT_C29265 NCIT_P350 "C17H19N3" @default.
- NCIT_C29265 NCIT_P366 "Mirtazapine" @default.
- NCIT_C29265 NCIT_P368 "CHEBI:6950" @default.
- NCIT_C29265 NCIT_P399 "559298" @default.
- NCIT_C29265 normalizedInformationContent "100" @default.
- NCIT_C29265 referenceCount "1" @default.
- NCIT_C29265 hasExactSynonym "MIRTAZAPINE" @default.
- NCIT_C29265 hasExactSynonym "Mirtazapine" @default.
- NCIT_C29265 hasExactSynonym "Remeron" @default.
- NCIT_C29265 hasExactSynonym "mirtazapine" @default.
- NCIT_C29265 inSubset NCIT_C116977 @default.
- NCIT_C29265 inSubset NCIT_C116978 @default.
- NCIT_C29265 inSubset NCIT_C176424 @default.
- NCIT_C29265 inSubset NCIT_C63923 @default.
- NCIT_C29265 type Class @default.
- NCIT_C29265 isDefinedBy ncit.owl @default.
- NCIT_C29265 label "Mirtazapine" @default.
- NCIT_C29265 subClassOf NCIT_C1908 @default.
- NCIT_C29265 subClassOf NCIT_C1909 @default.
- NCIT_C29265 subClassOf NCIT_C265 @default.
- NCIT_C29265 subClassOf NCIT_C29265 @default.
- NCIT_C29265 subClassOf NCIT_C78272 @default.