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- NCIT_C29268 IAO_0000115 "The furoate ester form of mometasone, a synthetic topical glucocorticoid receptor (GR) agonist with anti-inflammatory, anti-pruritic and vasoconstrictive properties. Upon administration, mometasone binds to cytoplasmic GRs and subsequently activates GR-mediated gene expression. This results in the synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators. Specifically, mometasone appears to induce phospholipase A2 inhibitory proteins, thereby controlling the release of the inflammatory precursor arachidonic acid from phospholipid membrane by phospholipase A2." @default.
- NCIT_C29268 NCIT_A6 NCIT_C66181 @default.
- NCIT_C29268 NCIT_A7 NCIT_C17071 @default.
- NCIT_C29268 NCIT_NHC0 "C29268" @default.
- NCIT_C29268 NCIT_P106 "Organic Chemical" @default.
- NCIT_C29268 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29268 NCIT_P107 "Mometasone Furoate" @default.
- NCIT_C29268 NCIT_P108 "Mometasone Furoate" @default.
- NCIT_C29268 NCIT_P207 "C0066700" @default.
- NCIT_C29268 NCIT_P210 "83919-23-7" @default.
- NCIT_C29268 NCIT_P302 "Sinusitis" @default.
- NCIT_C29268 NCIT_P319 "04201GDN4R" @default.
- NCIT_C29268 NCIT_P322 "CTRP" @default.
- NCIT_C29268 NCIT_P322 "FDA" @default.
- NCIT_C29268 NCIT_P325 "A drug that is used in a cream to treat certain skin conditions and in a nasal spray to treat sinus problems caused by allergies. It is being studied as a way to treat inflammation of the skin caused by radiation therapy. Elocon is a type of corticosteroid." @default.
- NCIT_C29268 NCIT_P329 "531049" @default.
- NCIT_C29268 NCIT_P330 "531049" @default.
- NCIT_C29268 NCIT_P350 "C27H30Cl2O6" @default.
- NCIT_C29268 NCIT_P366 "Mometasone_Furoate" @default.
- NCIT_C29268 NCIT_P368 "CHEBI:47564" @default.
- NCIT_C29268 NCIT_P399 "531049" @default.
- NCIT_C29268 normalizedInformationContent "100" @default.
- NCIT_C29268 referenceCount "1" @default.
- NCIT_C29268 hasExactSynonym "(11beta,16alpha)-9,21-Dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione" @default.
- NCIT_C29268 hasExactSynonym "Elocon" @default.
- NCIT_C29268 hasExactSynonym "MOMETASONE FUROATE" @default.
- NCIT_C29268 hasExactSynonym "Mometasone Furoate" @default.
- NCIT_C29268 hasExactSynonym "Nasonex" @default.
- NCIT_C29268 hasExactSynonym "Propel" @default.
- NCIT_C29268 hasExactSynonym "Sch-32088" @default.
- NCIT_C29268 hasExactSynonym "mometasone furoate" @default.
- NCIT_C29268 inSubset NCIT_C116977 @default.
- NCIT_C29268 inSubset NCIT_C116978 @default.
- NCIT_C29268 inSubset NCIT_C173381 @default.
- NCIT_C29268 inSubset NCIT_C173383 @default.
- NCIT_C29268 inSubset NCIT_C176424 @default.
- NCIT_C29268 inSubset NCIT_C63923 @default.
- NCIT_C29268 type Class @default.
- NCIT_C29268 isDefinedBy ncit.owl @default.
- NCIT_C29268 label "Mometasone Furoate" @default.
- NCIT_C29268 subClassOf NCIT_C147908 @default.
- NCIT_C29268 subClassOf NCIT_C1636 @default.
- NCIT_C29268 subClassOf NCIT_C1908 @default.
- NCIT_C29268 subClassOf NCIT_C1909 @default.
- NCIT_C29268 subClassOf NCIT_C211 @default.
- NCIT_C29268 subClassOf NCIT_C2364 @default.
- NCIT_C29268 subClassOf NCIT_C29268 @default.
- NCIT_C29268 subClassOf NCIT_C29505 @default.
- NCIT_C29268 subClassOf NCIT_C29629 @default.
- NCIT_C29268 subClassOf NCIT_C29639 @default.
- NCIT_C29268 subClassOf NCIT_C308 @default.
- NCIT_C29268 subClassOf NCIT_C548 @default.
- NCIT_C29268 subClassOf NCIT_C574 @default.