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- NCIT_C29287 IAO_0000115 "A sterile combination preparationscontaining neomycin sulfate, polymyxin B sulfate and bacitracin zinc, as the main active ingredients, for ophthalmic treatments. Polymyxin B sulfate, a polypeptide produced by Bacillus polymyxa, binds to the negatively charged phospholipids in the cell membrane, thereby altering the permeability of the bacterial cytoplasmic membrane. Neomycin sulfate, an aminoglycoside antibiotic, irreversibly binds to the bacterial 30S subunit proteins and 16S rRNA of ribosome, thereby causing misreading and inhibiting protein synthesis which results in bactericidal effect." @default.
- NCIT_C29287 NCIT_NHC0 "C29287" @default.
- NCIT_C29287 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29287 NCIT_P108 "Neomycin/Polymyxin B/Bacitracin Zinc Ophthalmic Ointment" @default.
- NCIT_C29287 NCIT_P207 "C3828836" @default.
- NCIT_C29287 NCIT_P366 "Neosporin_Ophthalmic" @default.
- NCIT_C29287 normalizedInformationContent "100" @default.
- NCIT_C29287 referenceCount "1" @default.
- NCIT_C29287 hasExactSynonym "Neomycin/Polymyxin B/Bacitracin Zinc Ophthalmic Ointment" @default.
- NCIT_C29287 hasExactSynonym "Neosporin Ophthalmic" @default.
- NCIT_C29287 type Class @default.
- NCIT_C29287 isDefinedBy ncit.owl @default.
- NCIT_C29287 label "Neomycin/Polymyxin B/Bacitracin Zinc Ophthalmic Ointment" @default.
- NCIT_C29287 subClassOf NCIT_C1908 @default.
- NCIT_C29287 subClassOf NCIT_C1909 @default.
- NCIT_C29287 subClassOf NCIT_C29287 @default.
- NCIT_C29287 subClassOf NCIT_C29629 @default.
- NCIT_C29287 subClassOf NCIT_C29637 @default.