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- NCIT_C29307 IAO_0000115 "A nonsteroidal anti-inflammatory drug (NSAID) derivative of oxazole-propionic acid with analgesic and antipyretic properties. As a first generation NSAID inhibitor, oxaprozin binds to and inactivates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of arachidonic acid to pro-inflammatory prostaglandins. When inhibiting COX-2, this agent may be effective in relieving pain and inflammation; when inhibiting COX-1, it may produce unacceptable gastrointestinal side effects. (NCI04)" @default.
- NCIT_C29307 NCIT_A5 NCIT_C48008 @default.
- NCIT_C29307 NCIT_NHC0 "C29307" @default.
- NCIT_C29307 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29307 NCIT_P108 "Oxaprozin" @default.
- NCIT_C29307 NCIT_P175 "310839" @default.
- NCIT_C29307 NCIT_P207 "C0069739" @default.
- NCIT_C29307 NCIT_P210 "21256-18-8" @default.
- NCIT_C29307 NCIT_P319 "MHJ80W9LRB" @default.
- NCIT_C29307 NCIT_P322 "FDA" @default.
- NCIT_C29307 NCIT_P350 "C18H15NO3" @default.
- NCIT_C29307 NCIT_P366 "Oxaprozin" @default.
- NCIT_C29307 normalizedInformationContent "100" @default.
- NCIT_C29307 referenceCount "1" @default.
- NCIT_C29307 hasExactSynonym "4,5-Diphenyl-2-oxazolepropionic Acid" @default.
- NCIT_C29307 hasExactSynonym "Daypro" @default.
- NCIT_C29307 hasExactSynonym "OXAPROZIN" @default.
- NCIT_C29307 hasExactSynonym "Oxaprozin" @default.
- NCIT_C29307 hasExactSynonym "Wy 21743" @default.
- NCIT_C29307 inSubset NCIT_C63923 @default.
- NCIT_C29307 type Class @default.
- NCIT_C29307 isDefinedBy ncit.owl @default.
- NCIT_C29307 label "Oxaprozin" @default.
- NCIT_C29307 subClassOf NCIT_C1323 @default.
- NCIT_C29307 subClassOf NCIT_C1908 @default.
- NCIT_C29307 subClassOf NCIT_C1909 @default.
- NCIT_C29307 subClassOf NCIT_C2198 @default.
- NCIT_C29307 subClassOf NCIT_C2356 @default.
- NCIT_C29307 subClassOf NCIT_C241 @default.
- NCIT_C29307 subClassOf NCIT_C257 @default.
- NCIT_C29307 subClassOf NCIT_C29307 @default.
- NCIT_C29307 subClassOf NCIT_C471 @default.
- NCIT_C29307 subClassOf NCIT_C78272 @default.