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- NCIT_C29333 IAO_0000115 "An dispiropiperazine derivative with potential cytostatic, anti-inflammatory and immune-suppressive properties. Although the exact mechanism of action of prospidin is not known, this agent was shown to interact with DNA, disrupting cell cycle at G2 phase, inhibiting phagocytic activity of monocytes and macrophage. Prospidin has good anti-lupus activity due to its immunosuppressive effects and was also used in refractory rheumatoid arthritis as an anti-rheumatic drug. (NCI04)" @default.
- NCIT_C29333 NCIT_NHC0 "C29333" @default.
- NCIT_C29333 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29333 NCIT_P108 "Prospidium Chloride" @default.
- NCIT_C29333 NCIT_P175 "166100" @default.
- NCIT_C29333 NCIT_P207 "C2355570" @default.
- NCIT_C29333 NCIT_P210 "23476-83-7" @default.
- NCIT_C29333 NCIT_P319 "7G733H6RES" @default.
- NCIT_C29333 NCIT_P322 "FDA" @default.
- NCIT_C29333 NCIT_P350 "C18H36Cl2N4O2.2Cl" @default.
- NCIT_C29333 NCIT_P366 "Prospidin" @default.
- NCIT_C29333 normalizedInformationContent "100" @default.
- NCIT_C29333 referenceCount "1" @default.
- NCIT_C29333 hasExactSynonym "3,12-Diaza-6,9-diazoniadispiro(5.2.5.2)hexadecane, 3,12-bis(3-chloro-2-hydroxypropyl)-, dichloride" @default.
- NCIT_C29333 hasExactSynonym "PROSPIDIUM CHLORIDE" @default.
- NCIT_C29333 hasExactSynonym "Prospidin" @default.
- NCIT_C29333 hasExactSynonym "Prospidine" @default.
- NCIT_C29333 hasExactSynonym "Prospidium Chloride" @default.
- NCIT_C29333 inSubset NCIT_C63923 @default.
- NCIT_C29333 type Class @default.
- NCIT_C29333 isDefinedBy ncit.owl @default.
- NCIT_C29333 label "Prospidium Chloride" @default.
- NCIT_C29333 subClassOf NCIT_C186664 @default.
- NCIT_C29333 subClassOf NCIT_C1908 @default.
- NCIT_C29333 subClassOf NCIT_C1909 @default.
- NCIT_C29333 subClassOf NCIT_C2163 @default.
- NCIT_C29333 subClassOf NCIT_C274 @default.
- NCIT_C29333 subClassOf NCIT_C2842 @default.
- NCIT_C29333 subClassOf NCIT_C29333 @default.
- NCIT_C29333 subClassOf NCIT_C308 @default.
- NCIT_C29333 subClassOf NCIT_C574 @default.