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- NCIT_C29344 IAO_0000115 "A synthetic agent, also known as IMPY, with antineoplastic properties. IMPY inhibits ribonucleotide reductase, an enzyme that converts ribonucleotides to deoxyribonucleotides during DNA synthesis; this agent specifically binds the smaller, nonheme-iron subunit of the enzyme. (NCI04)" @default.
- NCIT_C29344 NCIT_A32 NCIT_C1909 @default.
- NCIT_C29344 NCIT_NHC0 "C29344" @default.
- NCIT_C29344 NCIT_P106 "Organic Chemical" @default.
- NCIT_C29344 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29344 NCIT_P108 "Imidazole-Pyrazole" @default.
- NCIT_C29344 NCIT_P175 "51143" @default.
- NCIT_C29344 NCIT_P207 "C0045368" @default.
- NCIT_C29344 NCIT_P210 "6714-29-0" @default.
- NCIT_C29344 NCIT_P319 "MX6Z942BKY" @default.
- NCIT_C29344 NCIT_P322 "FDA" @default.
- NCIT_C29344 NCIT_P322 "GDC" @default.
- NCIT_C29344 NCIT_P366 "Pyrazole_Imidazole" @default.
- NCIT_C29344 NCIT_P375 "Imidazole-Pyrazole" @default.
- NCIT_C29344 NCIT_P98 "Inhibits the nonheme-iron subunit of ribonucleotide reductase" @default.
- NCIT_C29344 normalizedInformationContent "100" @default.
- NCIT_C29344 referenceCount "1" @default.
- NCIT_C29344 hasExactSynonym "2,3-Dihydro-1H-imidazo(1,2-b)pyrazole" @default.
- NCIT_C29344 hasExactSynonym "BRN 0742753" @default.
- NCIT_C29344 hasExactSynonym "IMPY" @default.
- NCIT_C29344 hasExactSynonym "Imidazole-Pyrazole" @default.
- NCIT_C29344 hasExactSynonym "Imidazolepyrazole" @default.
- NCIT_C29344 hasExactSynonym "PYRAZOLOIMIDAZOLE" @default.
- NCIT_C29344 inSubset NCIT_C128784 @default.
- NCIT_C29344 inSubset NCIT_C157711 @default.
- NCIT_C29344 inSubset NCIT_C157712 @default.
- NCIT_C29344 inSubset NCIT_C177537 @default.
- NCIT_C29344 inSubset NCIT_C63923 @default.
- NCIT_C29344 type Class @default.
- NCIT_C29344 isDefinedBy ncit.owl @default.
- NCIT_C29344 label "Imidazole-Pyrazole" @default.
- NCIT_C29344 subClassOf NCIT_C1908 @default.
- NCIT_C29344 subClassOf NCIT_C1909 @default.
- NCIT_C29344 subClassOf NCIT_C2150 @default.
- NCIT_C29344 subClassOf NCIT_C29344 @default.
- NCIT_C29344 subClassOf NCIT_C471 @default.