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- NCIT_C29346 IAO_0000115 "A substituted benzimidazole and proton pump inhibitor with antacid activity. Pantoprazole is a lipophilic weak base that crosses the parietal cell membrane and enters the acidic parietal cell canaliculus where it becomes protonated, producing the active metabolite sulphenamide, which forms an irreversible covalent bond with two sites of the H+/K+-ATPase enzyme located on the gastric parietal cell, thereby inhibiting both basal and stimulated gastric acid production." @default.
- NCIT_C29346 NCIT_A5 NCIT_C61877 @default.
- NCIT_C29346 NCIT_NHC0 "C29346" @default.
- NCIT_C29346 NCIT_P106 "Organic Chemical" @default.
- NCIT_C29346 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29346 NCIT_P108 "Pantoprazole" @default.
- NCIT_C29346 NCIT_P207 "C0081876" @default.
- NCIT_C29346 NCIT_P210 "102625-70-7" @default.
- NCIT_C29346 NCIT_P319 "D8TST4O562" @default.
- NCIT_C29346 NCIT_P322 "FDA" @default.
- NCIT_C29346 NCIT_P350 "C16H15F2N3O4S" @default.
- NCIT_C29346 NCIT_P366 "Pantoprazole" @default.
- NCIT_C29346 NCIT_P368 "CHEBI:7915" @default.
- NCIT_C29346 NCIT_R122 NCIT_C16484 @default.
- NCIT_C29346 NCIT_R122 NCIT_C16486 @default.
- NCIT_C29346 NCIT_R122 NCIT_C16554 @default.
- NCIT_C29346 NCIT_R122 NCIT_C16865 @default.
- NCIT_C29346 NCIT_R122 NCIT_C16946 @default.
- NCIT_C29346 NCIT_R122 NCIT_C17021 @default.
- NCIT_C29346 NCIT_R122 NCIT_C20027 @default.
- NCIT_C29346 NCIT_R122 NCIT_C25948 @default.
- NCIT_C29346 NCIT_R122 NCIT_C26548 @default.
- NCIT_C29346 NCIT_R122 NCIT_C28459 @default.
- NCIT_C29346 normalizedInformationContent "100" @default.
- NCIT_C29346 referenceCount "1" @default.
- NCIT_C29346 hasExactSynonym "PANTOPRAZOLE" @default.
- NCIT_C29346 hasExactSynonym "Pantoprazole" @default.
- NCIT_C29346 inSubset NCIT_C63923 @default.
- NCIT_C29346 type Class @default.
- NCIT_C29346 isDefinedBy ncit.owl @default.
- NCIT_C29346 label "Pantoprazole" @default.
- NCIT_C29346 subClassOf B95c7c31ce68541ab65ab18558e4c9af3 @default.
- NCIT_C29346 subClassOf Bd96d013a0bea6e0eefcfc670e7682d54 @default.
- NCIT_C29346 subClassOf NCIT_C1908 @default.
- NCIT_C29346 subClassOf NCIT_C1909 @default.
- NCIT_C29346 subClassOf NCIT_C29346 @default.
- NCIT_C29346 subClassOf NCIT_C29701 @default.
- NCIT_C29346 subClassOf NCIT_C29723 @default.
- NCIT_C29346 subClassOf NCIT_C78276 @default.