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- NCIT_C29358 IAO_0000115 "The maleate salt form of pheniramine, an alkylamine derivative with antihistaminic and vasodilatory properties. Pheniramine maleate binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of endothelium-derived relaxing factor, nitric oxide. Subsequent lack of activation of guanylyl cyclase through nitric oxide results in decreased cyclic GMP (cGMP) levels, thereby inhibiting constriction of smooth muscle tissue, and decreased capillary permeability and histamine-activated allergic reactions." @default.
- NCIT_C29358 NCIT_A6 NCIT_C61889 @default.
- NCIT_C29358 NCIT_NHC0 "C29358" @default.
- NCIT_C29358 NCIT_P106 "Organic Chemical" @default.
- NCIT_C29358 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29358 NCIT_P108 "Pheniramine Maleate" @default.
- NCIT_C29358 NCIT_P207 "C0887016" @default.
- NCIT_C29358 NCIT_P210 "132-20-7" @default.
- NCIT_C29358 NCIT_P319 "NYW905655B" @default.
- NCIT_C29358 NCIT_P322 "FDA" @default.
- NCIT_C29358 NCIT_P350 "C16H20N2.C4H4O4" @default.
- NCIT_C29358 NCIT_P366 "Pheniramine_Maleate" @default.
- NCIT_C29358 normalizedInformationContent "100" @default.
- NCIT_C29358 referenceCount "1" @default.
- NCIT_C29358 hasExactSynonym "PHENIRAMINE MALEATE" @default.
- NCIT_C29358 hasExactSynonym "Pheniramine Maleate" @default.
- NCIT_C29358 inSubset NCIT_C63923 @default.
- NCIT_C29358 type Class @default.
- NCIT_C29358 isDefinedBy ncit.owl @default.
- NCIT_C29358 label "Pheniramine Maleate" @default.
- NCIT_C29358 subClassOf NCIT_C1908 @default.
- NCIT_C29358 subClassOf NCIT_C1909 @default.
- NCIT_C29358 subClassOf NCIT_C29358 @default.
- NCIT_C29358 subClassOf NCIT_C29578 @default.
- NCIT_C29358 subClassOf NCIT_C308 @default.