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- NCIT_C29362 IAO_0000115 "A combination preparation containing phenylephrine, phenylpropanolamine and guaifenesin with decongestant and expectorant activities. Phenylephrine and phenylpropanolamine, direct-acting sympathicomimetic amines, activate alpha-adrenergic receptors in the nasal mucosa thereby causing vasoconstriction, reduces swelling of nasal mucous membranes and decreasing nasal and sinus congestion. Phenylpropanolamine also releases norepinephrine from its storage sites resulting in the effects already described. Guaifenesin increases respiratory tract mucus secretions and reduces the viscosity of mucus secretion by reducing adhesiveness and surface tension as well as increasing hydration of mucus, thereby increasing the efficiency of removing accumulated secretions from the upper and lower airways and making cough more productive." @default.
- NCIT_C29362 NCIT_NHC0 "C29362" @default.
- NCIT_C29362 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29362 NCIT_P108 "Phenylephrine/Phenylpropanolamine/Guaifenesin" @default.
- NCIT_C29362 NCIT_P207 "C1445789" @default.
- NCIT_C29362 NCIT_P366 "Phenylephedrine_Phenylpropanolamine_Guaifenesin" @default.
- NCIT_C29362 normalizedInformationContent "100" @default.
- NCIT_C29362 referenceCount "1" @default.
- NCIT_C29362 hasExactSynonym "Phenylephrine/Phenylpropanolamine/Guaifenesin" @default.
- NCIT_C29362 type Class @default.
- NCIT_C29362 isDefinedBy ncit.owl @default.
- NCIT_C29362 label "Phenylephrine/Phenylpropanolamine/Guaifenesin" @default.
- NCIT_C29362 subClassOf NCIT_C1908 @default.
- NCIT_C29362 subClassOf NCIT_C1909 @default.
- NCIT_C29362 subClassOf NCIT_C29362 @default.
- NCIT_C29362 subClassOf NCIT_C29629 @default.
- NCIT_C29362 subClassOf NCIT_C29630 @default.